Nicolas Cage Spider-Man Noir (voice)
Stan Lee Stan (voice), Thanks, In Memory Of, Executive Producer
Oscar Isaac Interesting Person #1 (voice)
Liev Schreiber Wilson Fisk (voice)
Chris Pine Peter Parker (voice)
Hailee Steinfeld Gwen Stacy (voice)
Kathryn Hahn Doc Ock (voice)
Natalie Morales Miss Calleros (voice)
Mahershala Ali Uncle Aaron (voice)
Jake Johnson Peter B. Parker (voice)
Zoë Kravitz Mary Jane (voice)
Greta Lee Interesting Person #2 (voice)
Brian Michael Bendis Executive Producer
Ty Dolla $ign Songs
Shameik Moore Miles Morales (voice)
Jaden Smith Songs
Brian Tyree Henry Jefferson Davis (voice)
Lake Bell Vanessa Fisk (voice)
Nicki Minaj Songs
Lex Lang Additional Voices (voice)
Luna Lauren Vélez Rio Morales (voice)
Marvin Jones III Tombstone (voice)
Phil Lord Producer, Story, Screenplay
John Mulaney Spider-Ham (voice)
Amy Pascal Producer
Scott Menville Additional Voices (voice)
Steve Ditko In Memory Of, Thanks
Lily Tomlin Aunt May (voice)
Jorma Taccone Green Goblin / Last Dude (voice)
Kimiko Glenn Peni Parker (voice)
Justin Shenkarow Additional Voices (voice)
Joaquín Cosío Scorpion (voice)
Chrystee Pharris Additional Voices (voice)
Post Malone Brooklyn Bystander (voice), Songs
Alex Hirsch Story Coordinator
Gary A. Hecker Foley Artist
Rodney Rothman Screenplay, Director
Daniel Pemberton Original Music Composer
Pierre Perifel Animation
Bob Persichetti Director
Avi Arad Producer
Arthur Ortiz Additional Voices (voice)
Rif Hutton Additional Voices (voice)
Jacqueline Pinol Additional Voices (voice)
Oscar Camacho Additional Voices (voice)
Christopher Miller Producer, Additional Voices (voice)
John Puglisi Story Artist
Melissa Sturm Additional Voices (voice)
Vince Staples Songs
Cody Cameron Story Artist
Justin K. Thompson Production Design
Heiko von Drengenberg Story Artist
Darcy Rose Byrnes Additional Voices (voice)
Bridget Hoffman Additional Voices (voice)
Michael Semanick Sound Re-Recording Mixer
Al Rodrigo Additional Voices (voice)
Peter Ramsey Director
Randy K. Singer Foley Mixer
Caitlin McKenna Additional Voices (voice), ADR Voice Casting
Shaboozey Songs
Christopher S. Aud Sound Effects Editor
Terrence Hardy Jr. Additional Voices (voice)
Lil Wayne Songs
Zac Campbell Compositing Artist
Juan Pope Additional Voices (voice)
Donna Lynn Leavy Additional Voices (voice)
Juan Pacheco Additional Voices (voice)
Nick Jaine Brooklyn Visions Teacher (voice)
Harrison Knight Additional Voices (voice)
Devika Parikh Additional Voices (voice)
David Werntz Sound Effects Editor
Tony Lamberti Sound Re-Recording Mixer