Nicolas Cage Spider-Man Noir (voice)
Oscar Isaac Interesting Person #1 (voice)
Stan Lee Stan (voice), Executive Producer, Thanks, In Memory Of
Hailee Steinfeld Gwen Stacy (voice)
Paul Lasaine Visual Development
Chris Pine Peter Parker (voice)
Mahershala Ali Uncle Aaron (voice)
Liev Schreiber Wilson Fisk (voice)
Kathryn Hahn Doc Ock (voice)
Lake Bell Vanessa Fisk (voice)
Natalie Morales Miss Calleros (voice)
Zoë Kravitz Mary Jane (voice)
Craig Kellman Character Designer
Greta Lee Interesting Person #2 (voice)
Jake Johnson Peter B. Parker (voice)
Bridget Hoffman Additional Voices (voice)
Gabe Hordos Visual Development
Joseph Sanfelippo Additional Voices (voice)
Post Malone Songs, Brooklyn Bystander (voice)
Nicki Minaj Songs
John Mulaney Spider-Ham (voice)
Stephan Franck Story Artist
Darcy Rose Byrnes Additional Voices (voice)
Tom Cohen Thanks
Mark Ackland Story Artist
Juan Pacheco Additional Voices (voice)
Arthur Ortiz Additional Voices (voice)
Lily Tomlin Aunt May (voice)
Matthew E. Taylor Dialogue Editor
Muneeb Rehman Brooklyn Visions Teacher (voice)
Luna Lauren Vélez Rio Morales (voice)
Phil Lord Screenplay, Producer, Story
Oscar Camacho Additional Voices (voice)
Avi Arad Producer
Joaquín Cosío Scorpion (voice)
Matthew Landon Editor
Juan Pope Additional Voices (voice)
Bob Persichetti Director
Miles Thompson Story Artist
Laide Agunbiade Lighting Artist, Compositing Artist
Jon Bruno Additional Voices (voice)
Arthur D. Noda Editor
André Lacroix Animation
Christopher Miller Additional Voices (voice), Producer
Brian Tyree Henry Jefferson Davis (voice)
Amy Pascal Producer
Warren Sroka Additional Voices (voice)
Omar Smith Character Designer
Alberto Mielgo Other
Jorma Taccone Green Goblin / Last Dude (voice)
Justin K. Thompson Production Design
Kimiko Glenn Peni Parker (voice)
Christina Steinberg Producer
David Gimenez Animation
Ian McQue Thanks
Justin Shenkarow Additional Voices (voice)
Shameik Moore Miles Morales (voice)
Cynthia Potvin Animation Coordinator
Rodney Rothman Screenplay, Director
Nideep Varghese Animation
Michael A. Reagan Sound Effects Editor
Jason Linere-White Additional Voices (voice)
Scott Menville Additional Voices (voice)
Jessica Mikayla Adams Brooklyn Friend (voice)
Devika Parikh Additional Voices (voice)
Cody Cameron Story Artist
Christopher S. Aud Sound Effects Editor
Harrison Knight Additional Voices (voice)
Tony Lamberti Sound Re-Recording Mixer
Melissa Sturm Additional Voices (voice)
Marvin Jones III Tombstone (voice)
Terrence Hardy Jr. Additional Voices (voice)