Nicolas Cage Spider-Man Noir (voice)
Shameik Moore Miles Morales (voice)
Oscar Isaac Interesting Person #1 (voice)
Hailee Steinfeld Gwen Stacy (voice)
Chris Pine Peter Parker (voice)
Liev Schreiber Wilson Fisk (voice)
Christopher S. Aud Sound Effects Editor
Natalie Morales Miss Calleros (voice)
Zoë Kravitz Mary Jane (voice)
Stan Lee Thanks, In Memory Of, Stan (voice), Executive Producer
Mahershala Ali Uncle Aaron (voice)
Darcy Rose Byrnes Additional Voices (voice)
Geoffrey G. Rubay Supervising Sound Editor
Luna Lauren Vélez Rio Morales (voice)
Jaden Smith Songs
Scott Menville Additional Voices (voice)
Greta Lee Interesting Person #2 (voice)
Kathryn Hahn Doc Ock (voice)
Jake Johnson Peter B. Parker (voice)
Gary A. Hecker Foley Artist
Shakira Ja'nai Paye Additional Voices (voice)
Brian Tyree Henry Jefferson Davis (voice)
Lake Bell Vanessa Fisk (voice)
Jorma Taccone Green Goblin / Last Dude (voice)
Brian Michael Bendis Executive Producer
Kimiko Glenn Peni Parker (voice)
Randy K. Singer Foley Mixer
James C.J. Williams Head of Layout
Justin K. Thompson Production Design
Cody Cameron Story Artist
Lily Tomlin Aunt May (voice)
Michael J. Broomberg Foley Artist
John Mulaney Spider-Ham (voice)
Michelle Jubilee Gonzalez Additional Voices (voice)
Heiko von Drengenberg Story Artist
Vivek 'Vic' Sharma Associate Editor
Benjamin L. Cook Sound Effects Editor
Phil Lord Story, Screenplay, Producer
Claudia Choi Brooklyn Visions Teacher (voice)
Jessica E. Smialek Post Production Supervisor
Alex Hirsch Story Coordinator
Jeffrey M. Thompson Visual Development
Christopher Miller Producer, Additional Voices (voice)
Caitlin McKenna Additional Voices (voice), ADR Voice Casting
Martin Campos Amoros Animation
Devika Parikh Additional Voices (voice)
Humberto Francisco Rosa Supervising Animator
Steve Ditko In Memory Of, Thanks
José Más Huertas Animation
Jacobo Pineiro Rumbo Animation
Nicki Minaj Songs
Post Malone Songs, Brooklyn Bystander (voice)
Pedro de la Llave Animation
Daniel Pemberton Original Music Composer
Booby Yoonsung Jeong Modeling
Marvin Jones III Tombstone (voice)
Victor G. Reano Animation
Courtney Peldon Additional Voices (voice)
Donna Lynn Leavy Additional Voices (voice)
Joaquín Cosío Scorpion (voice)
Rodney Rothman Screenplay, Director
Avi Arad Producer
Rif Hutton Additional Voices (voice)
Chrystee Pharris Additional Voices (voice)
Mary Hidalgo Casting
Sean Ari Peterson Animation
Tony Lamberti Sound Re-Recording Mixer
Jacqueline Pinol Additional Voices (voice)
Peter Ramsey Director
Bob Persichetti Director
Nathan Klein Orchestrator
June Christopher Additional Voices (voice)