Nicolas Cage Spider-Man Noir (voice)
Stan Lee Stan (voice), Thanks, In Memory Of, Executive Producer
Oscar Isaac Interesting Person #1 (voice)
Hailee Steinfeld Gwen Stacy (voice)
Natalie Morales Miss Calleros (voice)
Chris Pine Peter Parker (voice)
Liev Schreiber Wilson Fisk (voice)
Mahershala Ali Uncle Aaron (voice)
Kathryn Hahn Doc Ock (voice)
Greta Lee Interesting Person #2 (voice)
Jake Johnson Peter B. Parker (voice)
Zoë Kravitz Mary Jane (voice)
Brian Michael Bendis Executive Producer
Ty Dolla $ign Songs
Nicki Minaj Songs
Jaden Smith Songs
Shameik Moore Miles Morales (voice)
Brian Tyree Henry Jefferson Davis (voice)
Lake Bell Vanessa Fisk (voice)
Lex Lang Additional Voices (voice)
Luna Lauren Vélez Rio Morales (voice)
Phil Lord Producer, Story, Screenplay
Marvin Jones III Tombstone (voice)
Amy Pascal Producer
John Mulaney Spider-Ham (voice)
Scott Menville Additional Voices (voice)
Lily Tomlin Aunt May (voice)
Kimiko Glenn Peni Parker (voice)
Avi Arad Producer
Steve Ditko In Memory Of, Thanks
Justin Shenkarow Additional Voices (voice)
Joaquín Cosío Scorpion (voice)
Post Malone Brooklyn Bystander (voice), Songs
Jorma Taccone Green Goblin / Last Dude (voice)
Alex Hirsch Story Coordinator
Gary A. Hecker Foley Artist
Daniel Pemberton Original Music Composer
Pierre Perifel Animation
Rodney Rothman Screenplay, Director
Bob Persichetti Director
Arthur Ortiz Additional Voices (voice)
Rif Hutton Additional Voices (voice)
Jacqueline Pinol Additional Voices (voice)
Oscar Camacho Additional Voices (voice)
Peter Ramsey Director
Christopher Miller Producer, Additional Voices (voice)
John Puglisi Story Artist
Vince Staples Songs
Chrystee Pharris Additional Voices (voice)
Caitlin McKenna Additional Voices (voice), ADR Voice Casting
Darcy Rose Byrnes Additional Voices (voice)
Melissa Sturm Additional Voices (voice)
Justin K. Thompson Production Design
Bridget Hoffman Additional Voices (voice)
Cody Cameron Story Artist
Al Rodrigo Additional Voices (voice)
Shaboozey Songs
Michael Semanick Sound Re-Recording Mixer
Terrence Hardy Jr. Additional Voices (voice)
Lil Wayne Songs
Devika Parikh Additional Voices (voice)
Jose Luis Llado Porquer Animation
Zac Campbell Compositing Artist
Donna Lynn Leavy Additional Voices (voice)
Tony Lamberti Sound Re-Recording Mixer
Juan Pacheco Additional Voices (voice)
Nick Jaine Brooklyn Visions Teacher (voice)
Harrison Knight Additional Voices (voice)
Paul Lasaine Visual Development
David Werntz Sound Effects Editor
Christopher S. Aud Sound Effects Editor
Shakira Ja'nai Paye Additional Voices (voice)