Natasha Lyonne Mama Poot (voice)
Kurt Russell Ron (voice)
Hannah Waddingham Jezebeth (voice)
Rihanna Producer, Original Music Composer, Smurfette (voice)
John Goodman Papa Smurf (voice)
Nick Offerman Ken (voice)
Amy Sedaris Jaunty (voice)
Octavia Spencer Asmodius (voice)
Sandra Oh Moxie Smurf (voice)
Nick Kroll Chernobog (voice)
Conrad Vernon Butler (voice)
Randy Thom Sound Designer
Chris Miller Director, Grouchy Smurf / Camouflage Smurf (voice)
James Corden No Name (voice)
Jimmy Kimmel Tardigrade (voice)
Xolo Maridueña Brainy Smurf (voice)
JP Karliak Gargamel / Razamel (voice)
Alex Winter Hefty Smurf (voice)
Dan Levy Joel (voice)
Maya Erskine Vanity Smurf (voice)
Billie Lourd Worry Smurf (voice)
Gary Rizzo Sound Re-Recording Mixer
Tom Myers Supervising Sound Editor
Peyo Characters
Andrew Lary Executive Producer
Chris Prynoski Quiet Smurf / Way Back There Smurf / Shark Taming Smurf (voice)
Pete Chiappetta Executive Producer
Pam Brady Writer
Henry Jackman Original Music Composer
DJ Snake DJ Snake (voice)
Anthony Tittanegro Executive Producer
Rachel Butera Azrael / List Maker Smurf (voice)
Keisuke Hoashi Razamel Anime (voice)
Daisuke Tsuji No Name Anime (voice)
Peter Lyons Collister Director of Photography, Second Unit Director
Coya Elliott ADR Editor
Matthew Landon Editor
Marco Furbatto Art Direction
Marshmello Turtle (voice)
Gwyn Sannia First Assistant Director
Jonny Manganello Baker Smurf (voice)
Yuuki Luna Smurfette Anime (voice)
Tyler Peterson Bellhop (voice)
Danilo Bollettini Special Effects Technician
Rosario Pucciarelli Second Assistant Director
Chris Kazmier Visual Effects Supervisor
Andrew Babick Visual Effects Supervisor
Tyran "Ty Ty" Smith Producer
Arianna Palmucci Hair Designer
Margaret Wuller Art Direction
Ryan Naylor Calendar Smurf (voice)
Léa Elui Featured Paris Disco Dancer (voice)
Ryan Harris Producer
Maurizio Tiella Camera Operator
Jay Brown Producer
Hugo Miller Clumsy Smurf (voice)
Daniela Zorzetto Set Decoration
Edoardo Galeone Second Second Assistant Director
Giulia De Stefano Set Decoration
Flavia Battista Third Assistant Director
Spencer X Sound Effects Smurf (voice)