Nicolas Cage Spider-Man Noir (voice)
Oscar Isaac Miguel O'Hara (voice)
Daniel Kaluuya Hobie Brown (voice)
Hailee Steinfeld Gwen Stacy (voice)
Andy Samberg Ben Reilly (voice)
Mahershala Ali Uncle Aaron (voice)
Jason Schwartzman Spot (voice)
Shea Whigham George Stacy (voice)
Greta Lee LYLA (voice)
Jake Johnson Peter B. Parker (voice)
Amandla Stenberg Margo Kess (voice)
Issa Rae Jessica Drew (voice)
John Mulaney Spider-Ham (voice)
Luna Lauren Vélez Rio Morales (voice)
Phil Lord Producer, Writer
Karan Soni Pavitr Prabhakar (voice)
Avi Arad Producer
Bob Persichetti Director
Michael Lasker Visual Effects Supervisor
Christopher Miller Producer, Writer
Brian Tyree Henry Jeff Morales (voice)
Amy Pascal Producer
Jharrel Jerome Miles G. Morales (voice)
Justin K. Thompson Director
Kimiko Glenn Peni Parker (voice)
Christina Steinberg Executive Producer
Shameik Moore Miles Morales (voice)
Michael Andrews Editor
David Callaham Writer
Daniel Pemberton Original Music Composer
Alice Brooks Director of Photography
Jesús Alonso Iglesias Character Designer
Aditya Sood Executive Producer
Jinko Gotoh Producer
Vi-Dieu Nguyen Head of Story
Patrick O'Keefe Production Design
Jessica Berri Co-Producer
Erik Wiese Storyboard Artist
Samantha Suyi Lee Story Artist
Kaitlyn Fox Lighting Artist