David Eigenberg Nermal (voice)
Jennifer Love Hewitt Liz
Alan Cumming Persnikitty (voice)
Debra Messing Arlene (voice)
Nick Cannon Louis (voice)
Bill Murray Garfield (voice)
Stephen Tobolowsky Happy Chapman
Breckin Meyer Jon
Brad Garrett Luca (voice)
Richard Kind Dad Rat (voice)
Jimmy Kimmel Spanky (voice)
Alyson Stoner Kid Rat (voice)
Michael Monks Deputy Hopkins
Mel Rodriguez Security Officer
Evan Arnold Wendell
Christophe Beck Original Music Composer
John Davis Producer
Jerry Hauck Cop
Dean Cundey Director of Photography
Mathew Krentz Compositing Artist
Jim Davis Comic Book
Crystal the Monkey Pet Monkey (uncredited)
Peter Hewitt Director
Juliette Goglia Little Girl
Mark Christopher Lawrence Christopher Mello
Bill Hoag Roy the Lodge Member
Joel Cohen Screenplay
Alec Sokolow Screenplay
Ben Kronen Older Man
Barbara Anne Klein Stunts
Eve Brent Mrs. Baker
Risa Bramon Garcia Casting
Daamen J. Krall Announcer
Peter E. Berger Editor
Dan DeLeeuw Visual Effects Supervisor
Neil Machlis Executive Producer
Alec Hammond Production Design
Michael A. Stevenson Editor
Angie Jones Animation
Michele Imperato Stabile Co-Producer
Glenn Derry Pre-Visualization Supervisor
Brian Manis Executive Producer
Vanessa Campbell Miss Ace Hardware
Marie France Costume Design
Randee Reicher Dog Owner #2
Rufus Gifford Dog Owner #1
Brennan Dufresne Casting
Susan Moore Dog Owner #4
Joseph Edward Taylor Frank
Ryan McKasson Dog Owner #3