Jennifer Love Hewitt Liz
Brad Garrett Luca (voice)
Bill Murray Garfield (voice)
Christophe Beck Original Music Composer
Alan Cumming Persnikitty (voice)
Debra Messing Arlene (voice)
Nick Cannon Louis (voice)
Stephen Tobolowsky Happy Chapman
Breckin Meyer Jon
Jimmy Kimmel Spanky (voice)
Richard Kind Dad Rat (voice)
Alyson Stoner Kid Rat (voice)
Michael Monks Deputy Hopkins
David Eigenberg Nermal (voice)
Mel Rodriguez Security Officer
Evan Arnold Wendell
Jerry Hauck Cop
Crystal the Monkey Pet Monkey (uncredited)
John Davis Producer
Jim Davis Comic Book
Dean Cundey Director of Photography
Mark Christopher Lawrence Christopher Mello
Peter Hewitt Director
Juliette Goglia Little Girl
Bill Hoag Roy the Lodge Member
Joel Cohen Screenplay
Alec Sokolow Screenplay
Ben Kronen Older Man
Barbara Anne Klein Stunts
Eve Brent Mrs. Baker
Risa Bramon Garcia Casting
Daamen J. Krall Announcer
Dan DeLeeuw Visual Effects Supervisor
Peter E. Berger Editor
Alec Hammond Production Design
Neil Machlis Executive Producer
Michael A. Stevenson Editor
Angie Jones Animation
Mathew Krentz Compositing Artist
Michele Imperato Stabile Co-Producer
Glenn Derry Pre-Visualization Supervisor
Brian Manis Executive Producer
Vanessa Campbell Miss Ace Hardware
Marie France Costume Design
Randee Reicher Dog Owner #2
Rufus Gifford Dog Owner #1
Brennan Dufresne Casting
Susan Moore Dog Owner #4
Joseph Edward Taylor Frank
Ryan McKasson Dog Owner #3