Stephen Tobolowsky Happy Chapman
Jennifer Love Hewitt Liz
Alan Cumming Persnikitty (voice)
Richard Kind Dad Rat (voice)
David Eigenberg Nermal (voice)
Debra Messing Arlene (voice)
Bill Murray Garfield (voice)
Christophe Beck Original Music Composer
Nick Cannon Louis (voice)
Mel Rodriguez Security Officer
Breckin Meyer Jon
Brad Garrett Luca (voice)
Jimmy Kimmel Spanky (voice)
Alyson Stoner Kid Rat (voice)
Michael Monks Deputy Hopkins
Crystal the Monkey Pet Monkey (uncredited)
Mark Christopher Lawrence Christopher Mello
Evan Arnold Wendell
Jerry Hauck Cop
Dean Cundey Director of Photography
John Davis Producer
Jim Davis Comic Book
Peter Hewitt Director
Juliette Goglia Little Girl
Bill Hoag Roy the Lodge Member
Joel Cohen Screenplay
Mathew Krentz Compositing Artist
Alec Sokolow Screenplay
Ben Kronen Older Man
Barbara Anne Klein Stunts
Eve Brent Mrs. Baker
Dan DeLeeuw Visual Effects Supervisor
Risa Bramon Garcia Casting
Daamen J. Krall Announcer
Peter E. Berger Editor
Neil Machlis Executive Producer
Michael A. Stevenson Editor
Alec Hammond Production Design
Angie Jones Animation
Brennan Dufresne Casting
Glenn Derry Pre-Visualization Supervisor
Brian Manis Executive Producer
Vanessa Campbell Miss Ace Hardware
Marie France Costume Design
Michele Imperato Stabile Co-Producer
Randee Reicher Dog Owner #2
Rufus Gifford Dog Owner #1
Susan Moore Dog Owner #4
Joseph Edward Taylor Frank
Ryan McKasson Dog Owner #3