Bob Hoskins Eddie Valiant
Joanna Cassidy Dolores
Steven Spielberg Executive Producer
Amy Irving Jessica Rabbit (singing voice) (uncredited)
Christopher Lloyd Judge Doom
June Foray Wheezy / Lena Hyena (voice)
Russi Taylor Minnie Mouse / Birds (voice)
Frank Welker Dumbo (voice) (uncredited)
Betsy Brantley Jessica's Performance Model
Kathleen Turner Jessica Rabbit (voice) (uncredited)
Brian Smrz Stunts
Robert Zemeckis Director
Ken Chase Key Makeup Artist
Jim Cummings Bullet #2 (voice)
Frank Sinatra Singing Sword (voice) (archive sound)
Charles L. Campbell Supervising Sound Editor
Nancy Cartwright Dipped Shoe (voice) (uncredited)
Mel Blanc Daffy Duck / Tweety / Bugs Bunny / Sylvester / Porky Pig (voice)
Jack Angel Additional Voices (voice) (uncredited)
Alan Silvestri Original Music Composer
Claire Williams Animation Manager
Uli Meyer Animation
Terry Jackson Stunts
Vera Pacheco Animation
Richard Ridings Angelo
Charles Fleischer Roger Rabbit / Benny The Cab / Greasy / Psycho (voice)
Kathleen Kennedy Executive Producer
Joe Alaskey Yosemite Sam / Foghorn Leghorn (voice)
Joel Silver Raoul
Mickie McGowan Mooing Cow / Flying Witch (voice) (uncredited)
Mae Questel Betty Boop (voice)
Tony Anselmo Donald Duck (voice)
Charles Croughwell Stunts
Andy Bradford Stunts
Dean Cundey Director of Photography
Frank Marshall Producer
Tina Simmons Ink and Paint Club Patron (uncredited)
Simon Wells Supervising Animator
April Winchell Mrs. Herman (voice)
Morgan Deare Editor / Gorilla (voice)
David L. Lander Smart Ass (voice)
Don Hahn Associate Producer
Chris Lyons Special Effects Makeup Artist
Pat Buttram Bullet #1 (voice)
Alan Tilvern R.K. Maroon
Edwin Craig Arthritic Cowboy
Steve Starkey Associate Producer
Robert Watts Producer
Ken Ralston Visual Effects Supervisor
Tom Sito Animation
Peter Howitt Set Decoration
Billy J. Mitchell Forensic #2
Michael Lantieri Special Effects Supervisor
Lou Hirsch Baby Herman (voice)
Fred Newman Stupid (voice)
Joanna Johnston Costume Design
Jason White Stunts
Wayne Allwine Mickey Mouse (voice)
Rocky Taylor Stunts
James Baxter Animation
Richard LeParmentier Lt. Santino
Stubby Kaye Marvin Acme
Peter S. Seaman Screenplay
Martin Cohen Post Production Supervisor
Terry Walsh Stunts
Adam Somner Production Runner
Jeffrey Price Screenplay
Del Baker Stunts
Richard Williams Droopy (voice), Animation Director
Arthur Schmidt Editor
Ed Herlihy Newscaster
Graham Churchyard Assistant Costume Designer