Tom Hanks Dr. Henry Goose / Hotel Manager / Isaac Sachs / Dermot Hoggins / Cavendish Look-a-Like Actor / Zachry
Hugo Weaving Haskell Moore / Tadeusz Kesselring / Bill Smoke / Nurse Noakes / Boardman Mephi / Old Georgie
Natalie Portman Thanks
David Gyasi Autua / Lester Rey / Duophsyte
Hugh Grant Rev. Giles Horrox / Hotel Heavy / Lloyd Hooks / Denholme Cavendish / Seer Rhee / Kona Chief
Halle Berry Native Woman / Jocasta Ayrs / Luisa Rey / Indian Party Guest / Ovid / Meronym
James D'Arcy Young Rufus Sixsmith / Old Rufus Sixsmith / Nurse James / Archivist
Zhu Zhu Megan Sixsmith / 12th Star Clone
Keith David Kupaka / Joe Napier / An-kor Apis / Prescient
Jim Broadbent Captain Molyneux / Vyvyan Ayrs / Timothy Cavendish / Korean Musician / Prescient 2
Zhou Xun Talbot / Hotel Manager / Yoona-939 / Rose
Susan Sarandon Madame Horrox / Older Ursula / Yusouf Suleiman / Abbess
Lana Wachowski Producer, Director, Screenplay
Bae Doona Tilda / Megan's Mom / Mexican Woman / Sonmi-451 / Sonmi-351 / Sonmi Prostitute
Ben Whishaw Cabin Boy / Robert Frobisher / Store Clerk / Georgette / Tribesman
Jim Sturgess Adam Ewing / Poor Hotel Guest / Megan's Dad / Highlander / Hae-Joo Chang / Adam / Zachry Brother-in-Law
David Scheunemann Art Direction
Alistair Petrie Haskell Moore's Dinner Guest / Musician / Felix Finch / Lascivious Businessman
Martin Wuttke Mr. Boerhaave / Guard / Leary the Healer
Lilly Wachowski Director, Screenplay, Producer
Tom Tykwer Director, Music, Producer, Original Music Composer, Screenplay
Andrew Havill Mr. Hotchkiss
Sylvestra Le Touzel Haskell Moore's Dinner Guest / Nurse Judd / Aide in Slaughtership
Götz Otto Groundsman Withers
Douglas Bloom CG Supervisor
Dan Glass Visual Effects
Marcus Loges Co-Producer
Lora Kennedy Casting
Steve Summersgill Art Direction
Jon Donahue Moore's Accountant / Finch's Friend (uncredited)
Ben O'Brien Compositing Supervisor
Kym Barrett Costume Design
Can Aydin Stunts
Gary McCormack Crane Operator
Terry Needham First Assistant Director
Johnny Klimek Original Music Composer
Daniele Massaccesi Camera Operator, Steadicam Operator
Niall Greig Fulton Haskell Moore's Dinner Guest / Mozza Hoggins
Lucinda Syson Casting
Robert Fyfe Old Salty Dog / Mr. Meeks / Prescient 1
Phong Giang Stunts
Louis Dempsey Haskell Moore's Dinner Guest / Jarvis Hoggins
Siân Richards Makeup Artist
Roberto Malerba Co-Producer
Amanda Walker Veronica
Chris Lyons Special Effects Makeup Artist
Jeremy Braben Aerial Director of Photography
Reinhold Heil Original Music Composer
Michael Miller ADR Mixer
Liam Byrne Armorer
John Chong Executive Producer
Alessandro Cioffi Visual Effects Supervisor
Pierre-Yves Gayraud Costume Design
Allison Paul Visual Effects Coordinator
Ralph Riach Ernie
Claus Wehlisch Editor
Olivier Dumont Visual Effects Art Director
David Mitchell Union Spy, Novel
Angela Barson Visual Effects Supervisor
Drew Jones Visual Effects Production Manager
Lars Ginzel Sound Re-Recording Mixer
Jeremy Woodhead Prosthetic Designer, Makeup Designer
Paula Price Makeup Artist, Hairstylist
Marie Charlotte Matthaei Set Dresser
Philip Lee Executive Producer
Mario Spanna Libra Head Technician
Hanse Warns Foley Mixer
Sherry Hitch Digital Compositor
Guillem Huertas Aerial Camera
Uwe Schott Executive Producer
Florian Emmerich Camera Operator
Katy Karrenbauer Axwoman