Tom Hanks Dr. Henry Goose / Hotel Manager / Isaac Sachs / Dermot Hoggins / Cavendish Look-a-Like Actor / Zachry
Natalie Portman Thanks
Keith David Kupaka / Joe Napier / An-kor Apis / Prescient
Halle Berry Native Woman / Jocasta Ayrs / Luisa Rey / Indian Party Guest / Ovid / Meronym
Hugo Weaving Haskell Moore / Tadeusz Kesselring / Bill Smoke / Nurse Noakes / Boardman Mephi / Old Georgie
Hugh Grant Rev. Giles Horrox / Hotel Heavy / Lloyd Hooks / Denholme Cavendish / Seer Rhee / Kona Chief
Ben Whishaw Cabin Boy / Robert Frobisher / Store Clerk / Georgette / Tribesman
Zhu Zhu Megan Sixsmith / 12th Star Clone
Susan Sarandon Madame Horrox / Older Ursula / Yusouf Suleiman / Abbess
Bae Doona Tilda / Megan's Mom / Mexican Woman / Sonmi-451 / Sonmi-351 / Sonmi Prostitute
Zhou Xun Talbot / Hotel Manager / Yoona-939 / Rose
James D'Arcy Young Rufus Sixsmith / Old Rufus Sixsmith / Nurse James / Archivist
Jim Broadbent Captain Molyneux / Vyvyan Ayrs / Timothy Cavendish / Korean Musician / Prescient 2
Lilly Wachowski Director, Screenplay, Producer
Jim Sturgess Adam Ewing / Poor Hotel Guest / Megan's Dad / Highlander / Hae-Joo Chang / Adam / Zachry Brother-in-Law
Alistair Petrie Haskell Moore's Dinner Guest / Musician / Felix Finch / Lascivious Businessman
David Gyasi Autua / Lester Rey / Duophsyte
Sylvestra Le Touzel Haskell Moore's Dinner Guest / Nurse Judd / Aide in Slaughtership
Lana Wachowski Producer, Director, Screenplay
Tom Tykwer Director, Music, Producer, Original Music Composer, Screenplay
Andrew Havill Mr. Hotchkiss
Dan Glass Visual Effects
John Chong Executive Producer
Götz Otto Groundsman Withers
Niall Greig Fulton Haskell Moore's Dinner Guest / Mozza Hoggins
Can Aydin Stunts
Martin Wuttke Mr. Boerhaave / Guard / Leary the Healer
Robert Fyfe Old Salty Dog / Mr. Meeks / Prescient 1
Chris Lyons Special Effects Makeup Artist
Jeremy Woodhead Prosthetic Designer, Makeup Designer
Jon Donahue Moore's Accountant / Finch's Friend (uncredited)
Victor Solé Mr. Roderick
Ralph Riach Ernie
Kym Barrett Costume Design
Amanda Walker Veronica
Michael Miller ADR Mixer
Philip Lee Executive Producer
Alexander Rodnyansky Producer
Lucinda Syson Casting
John Toll Director of Photography
Kurt Van Der Basch Storyboard Artist
Siân Richards Makeup Artist
Charlie Revai Supervising Art Director
Hanse Warns Foley Mixer
Travis Baumann Compositing Supervisor
Katy Karrenbauer Axwoman
Steve Summersgill Art Direction
Daniele Massaccesi Camera Operator, Steadicam Operator
Alexander Berner Editor
Pearry Reginald Teo Executive Producer
Frank Kruse Sound Designer
Liam Byrne Armorer
Marie Rönnebeck Ursula's Daughter
Marc Kolbe Visual Effects Producer
Thomas Kügel Vater
George Hull Conceptual Design
Damian Anderson Production Coordinator
Carsten Richter Foley Artist
Shaun Lawton Secretary
Reinhold Heil Original Music Composer
Iain Eyre Supervising Dialogue Editor, Supervising ADR Editor
Cristina Patterson Contact Lens Painter, Contact Lens Designer
Heike Merker Makeup Supervisor, Hair Supervisor
Daniela Skala Makeup Artist, Hairstylist
Claus Wehlisch Editor
Guillem Huertas Aerial Camera
Lars Ginzel Sound Re-Recording Mixer
Louis Dempsey Haskell Moore's Dinner Guest / Jarvis Hoggins
Peter Lam Kin-Ngok Executive Producer, Co-Producer
Terry Needham First Assistant Director
Stephane Ceretti Visual Effects Supervisor
Peter Walpole Set Decoration