Christina Ricci Vexy (voice)
Jacob Tremblay Blue Winslow
Brendan Gleeson Victor Doyle
George López Grouchy Smurf (voice)
Alan Cumming Gutsy Smurf (voice)
Frank Welker Azrael (voice)
Neil Patrick Harris Patrick Winslow
Hank Azaria Gargamel
Jayma Mays Grace Winslow
Fred Armisen Brainy Smurf (voice)
Katy Perry Smurfette (voice)
Kenan Thompson Greedy Smurf (voice)
Shaquille O'Neal Smooth Smurf (voice)
Anton Yelchin Clumsy Smurf (voice)
JB Smoove Hackus (voice)
Tom Kane Narrator Smurf (voice)
Becky G Songs
John Oliver Vanity Smurf (voice)
Patrick Sabongui Candy Man
B.J. Novak Baker Smurf (voice)
Jeff Foxworthy Handy Smurf (voice)
Paul Reubens Jokey Smurf (voice)
Jimmy Kimmel Passive-Aggressive Smurf (voice)
John Kassir Crazy Smurf (voice)
Raja Gosnell Director
David Ronn Screenplay, Story
Mario López Social Smurf (voice)
Karey Kirkpatrick Screenplay
Erika Rosenbaum Pregnant Mom
David N. Weiss Screenplay, Story
Adam Wylie Panicky Smurf (voice)
Alain Moussi Stunts
J. David Stem Story, Screenplay
Mylène Dinh-Robic Hotel Assistant Manager
Joel McCrary Farmer Smurf (voice)
Gary Basaraba Hefty Smurf (voice)
Carolina Bartczak Peanut Mom
Sean Kenin Smurf Voice #1 (voice)
David Rubin Casting
Shaun White Clueless Smurf (voice)
Martin Doepner Additional Third Assistant Director
G.A. Aguilar Second Unit Director, Stunt Coordinator
Jay Scherick Screenplay, Story
Beatrice Rosen Pregnant Model
Karim Babin Room Service Waiter
Ruth Chiang Single Mom
James A. Woods Peanut Father
Todd Tucker Makeup Department Head
Nancy O'Dell Nancy O'Dell
Phil Meheux Director of Photography
Jordan Kerner Producer
Patricia Summersett Smurf Voice #2 (voice)
Raphaël Benoliel Co-Producer
Heitor Pereira Original Music Composer
Randi Wells Casting
Gaston Morrison New York Taxi Driver
Michael Parks Animation
Juliette Ménager Casting
Andrea Kenyon Casting
Peyo Characters, Comic Book
Ezra Swerdlow Executive Producer
Rita Ryack Costume Design
Patrick Baby Palais Garnier Security Guard
Dusan Dukic Curious Dad
Lea Lambert Production Manager
Bill Boes Production Design
Benita Allen Co-Producer, First Assistant Director
Jonathan Winters Papa Smurf (voice)
Véronique Marchessault Costume Design
Sabrina Plisco Associate Producer, Editor
Michele Laliberte Supervising Art Director
Maricel Pagulayan Associate Producer