Christina Ricci Vexy (voice)
Alan Cumming Gutsy Smurf (voice)
Fred Armisen Brainy Smurf (voice)
Brendan Gleeson Victor Doyle
Jacob Tremblay Blue Winslow
Hank Azaria Gargamel
Neil Patrick Harris Patrick Winslow
Frank Welker Azrael (voice)
Tom Kane Narrator Smurf (voice)
B.J. Novak Baker Smurf (voice)
Jayma Mays Grace Winslow
Sinan Saber Third Assistant Director
G.A. Aguilar Second Unit Director, Stunt Coordinator
Jimmy Kimmel Passive-Aggressive Smurf (voice)
Kenan Thompson Greedy Smurf (voice)
Mario López Social Smurf (voice)
Patrick Sabongui Candy Man
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
Alain Moussi Stunts
George López Grouchy Smurf (voice)
Joel McCrary Farmer Smurf (voice)
Becky G Songs
Shaquille O'Neal Smooth Smurf (voice)
Paul Reubens Jokey Smurf (voice)
Mylène Dinh-Robic Hotel Assistant Manager
Adam Wylie Panicky Smurf (voice)
Jeff Foxworthy Handy Smurf (voice)
John Oliver Vanity Smurf (voice)
Sean Kenin Smurf Voice #1 (voice)
Véronique Marchessault Costume Design
Raphaël Benoliel Co-Producer
JB Smoove Hackus (voice)
Carolina Bartczak Peanut Mom
Nancy Honeycutt Production Supervisor
Phil Meheux Director of Photography
Shaun White Clueless Smurf (voice)
Jonathan Winters Papa Smurf (voice)
Raja Gosnell Director
Nancy O'Dell Nancy O'Dell
Karey Kirkpatrick Screenplay
John Kassir Crazy Smurf (voice)
Heitor Pereira Original Music Composer
Ruth Chiang Single Mom
Todd Tucker Makeup Department Head
Beatrice Rosen Pregnant Model
David N. Weiss Screenplay, Story
Gary Basaraba Hefty Smurf (voice)
J. David Stem Story, Screenplay
Vanessa Matsui Mother with Camera
Juliette Ménager Casting
Bill Boes Production Design
Peyo Characters, Comic Book
Erika Rosenbaum Pregnant Mom
Dusan Dukic Curious Dad
Gaston Morrison New York Taxi Driver
Andrea Kenyon Casting
Austin Mahone Songs
Patrick Baby Palais Garnier Security Guard
James A. Woods Peanut Father
Randi Wells Casting
Karim Babin Room Service Waiter
Vincent Gingras-Liberali Art Direction
David Ronn Screenplay, Story
David Rubin Casting
Patricia Summersett Smurf Voice #2 (voice)
Ezra Swerdlow Executive Producer
Michael Parks Animation
Henri Pardo Father-to-Be
David E. Hall Post Production Supervisor
Jay Scherick Screenplay, Story
Bruno Paviot Hotel Desk Manager