Christina Ricci Vexy (voice)
Brendan Gleeson Victor Doyle
Jacob Tremblay Blue Winslow
Paul Reubens Jokey Smurf (voice)
Hank Azaria Gargamel
Frank Welker Azrael (voice)
JB Smoove Hackus (voice)
Alan Cumming Gutsy Smurf (voice)
George López Grouchy Smurf (voice)
Neil Patrick Harris Patrick Winslow
Fred Armisen Brainy Smurf (voice)
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
Jayma Mays Grace Winslow
Kenan Thompson Greedy Smurf (voice)
Adam Wylie Panicky Smurf (voice)
John Oliver Vanity Smurf (voice)
Patrick Sabongui Candy Man
Jimmy Kimmel Passive-Aggressive Smurf (voice)
James A. Woods Peanut Father
B.J. Novak Baker Smurf (voice)
Becky G Songs
Shaquille O'Neal Smooth Smurf (voice)
Alain Moussi Stunts
Karey Kirkpatrick Screenplay
John Kassir Crazy Smurf (voice)
Sean Kenin Smurf Voice #1 (voice)
Tom Kane Narrator Smurf (voice)
Joel McCrary Farmer Smurf (voice)
J. David Stem Story, Screenplay
Jonathan Winters Papa Smurf (voice)
Mario López Social Smurf (voice)
Nancy O'Dell Nancy O'Dell
David N. Weiss Screenplay, Story
Mylène Dinh-Robic Hotel Assistant Manager
Carolina Bartczak Peanut Mom
Peyo Characters, Comic Book
Jay Scherick Screenplay, Story
Gary Basaraba Hefty Smurf (voice)
Beatrice Rosen Pregnant Model
Raja Gosnell Director
Bruno Paviot Hotel Desk Manager
David Rubin Casting
David Ronn Screenplay, Story
Gaston Morrison New York Taxi Driver
Jeff Foxworthy Handy Smurf (voice)
Heitor Pereira Original Music Composer
Patrick Baby Palais Garnier Security Guard
Shaun White Clueless Smurf (voice)
Michael Parks Animation
Sabrina Plisco Associate Producer, Editor
G.A. Aguilar Second Unit Director, Stunt Coordinator
Erika Rosenbaum Pregnant Mom
Phil Meheux Director of Photography
Andrea Kenyon Casting
Randi Wells Casting
Ruth Chiang Single Mom
Todd Tucker Makeup Department Head
Raphaël Benoliel Co-Producer
Karim Babin Room Service Waiter
Dusan Dukic Curious Dad
Rita Ryack Costume Design
David E. Hall Post Production Supervisor
Vincent Gingras-Liberali Art Direction
Aaron Williams VFX Artist
Maricel Pagulayan Associate Producer
Ezra Swerdlow Executive Producer
Juliette Ménager Casting
Martin Doepner Additional Third Assistant Director
Lea Lambert Production Manager
Juan Miguel Vadell Animation
Patricia Summersett Smurf Voice #2 (voice)