Jackie Chan Splinter (voice)
Paul Rudd Mondo Gecko (voice)
Giancarlo Esposito Baxter Stockman (voice)
Rose Byrne Leatherhead (voice)
John Cena Rocksteady (voice)
Seth Rogen Story, Bebop (voice), Screenplay, Producer
Maya Rudolph Cynthia Utrom (voice)
Ayo Edebiri April O'Neil (voice)
Matthew Broderick Ferris Bueller (archive footage) (uncredited)
Ice Cube Superfly (voice)
Evan Goldberg Story, Screenplay, Producer
Michael Badalucco Bad Bernie (voice)
David Faustino Normal Nate (voice)
Hannibal Buress Genghis Frog (voice)
Alex Hirsch Bossy Goon / Scumbug (voice)
Natasia Demetriou Wingnut (voice)
Post Malone Ray Fillet (voice)
Trent Reznor Original Music Composer
Atticus Ross Original Music Composer
Mark Mangini Supervising Sound Editor, Sound Designer, Sound Re-Recording Mixer
Peter Laird Characters
Kevin Eastman Characters, Good Human (voice)
Danny Mastrogiorgio Toupee Tom / Police Officer (voice)
Nicolas Cantu Leonardo (voice)
Brady Noon Raphael (voice)
Dan Hernandez Screenplay
Jimmy Donaldson Times Square Guy (voice)
Shamon Brown Jr. Michelangelo (voice)
Michael Semanick Sound Re-Recording Mixer
John Capodice Cab Driver (voice)
Gabe Hilfer Music Supervisor
Mike Rianda Paycheck Goon / Chop Shop Boss / Ratatouille Guard (voice)
Eric Kissack Additional Editing
Rich Delia Original Casting
Jeff Rowe Director, Story, Man Who Loves Being Young and Free to Go Places (voice), Screenplay
James Weaver Producer
Brendan O'Brien Story
Derek Wilson Spider (voice)
Benji Samit Screenplay
Dempsey Pappion Bald Bronson (voice)
Chelsea Body Foley Mixer
Jacob Streilein Story Artist
Adel Sabi Character Designer
Julien Perron Story Artist
Josh Fagen Executive Producer
Jeffrey M. Thompson Visual Development
Andia Winslow TV Anchor (voice)
Peter Foltz Story Artist
Julien Meesters Executive Producer
Jacob Flack Sound Effects Editor
Chloé Nicolay Storyboard Artist, Story Artist
David Carrière Lead Animator
Kyler Spears Co-Director, Apologetic Goon (voice)
Sang Yup Lee Story Artist
J.J. Villard Visual Development
Adam Richards Casting Associate
Micah Abbey Donatello (voice)
Christopher Bonis Sound Effects Editor
Woodrow White Lead Character Designer
Arthur Fong Art Direction
David Bleich Visual Development
Kevin Jung Foley Editor
Jesse Dodd ADR Mixer
Isabella Spadone Story Artist
Yashar Kassai Production Design
James A. Castillo Character Designer
Natalie Canizares Sign My Baby Mom (voice)
Noel Gibson Responding Police Officer / Military Advisor (voice)
Charlie Parisi Story Artist
Linda Lamontagne Additional Casting
Greg Levitan Gecko Goon (voice), Editor
Gabriel Lin Head of Story