Natalia Castellanos Additional Voices (voice)
Oscar Isaac Miguel O'Hara (voice)
Hailee Steinfeld Gwen Stacy (voice)
Andrew Garfield Peter Parker (archive footage)
J.K. Simmons J. Jonah Jameson (voice)
Andy Samberg Ben Reilly (voice)
Kathryn Hahn Doc Ock (voice)
Jason Schwartzman Spot (voice)
Rachel Dratch Ms. Weber (voice)
Jack Quaid Peter Parker (voice)
Amandla Stenberg Margo Kess: Spider-Byte (voice)
Shea Whigham George Stacy (voice)
Taran Killam Web-Slinger (voice)
Daniel Kaluuya Hobie Brown (voice)
Karan Soni Pavitr Prabhakar (voice)
Ayo Edebiri Glory (voice)
Greta Lee LYLA (voice)
Mahershala Ali Uncle Aaron (voice)
Elizabeth Perkins May / Quippy Spider-Person (voice)
Luna Lauren Velez Rio Morales (voice)
Jake Johnson Peter B. Parker (voice)
Donald Glover Aaron Davis
Hasan Minhaj Thanks
Issa Rae Jessica Drew (voice)
David Michie Additional Voices (voice)
Brian Tyree Henry Jeff Morales (voice)
Jorma Taccone Adriano Tumino / '67 (voice)
Rodney Rothman Executive Producer
Kimiko Glenn Peni Parker (voice) (uncredited)
Shameik Moore Miles Morales (voice)
Warren Sroka Additional Voices (voice)
David Callaham Writer
Josh Keaton Spectacular Spider-Man (voice)
Yuri Lowenthal Insomniac Spider-Man (voice)
Ben Pronsky Additional Voices (voice)
Jeff Loveness Thanks
Geoffrey G. Rubay Supervising Sound Editor
Mallory Mahar Compositing Lead
Chris Mitchell Story Artist
Arthur Ortiz Additional Voices (voice)
Bob Persichetti Executive Producer
Kier Lehman Music Supervisor
Atsuko Okatsuka Yuri (voice)
Christian Hejnal Line Producer
Oscar Camacho Additional Voices (voice)
Alaa Afifeh Animation
Gerard Manresa Ortega Animation
Jharrel Jerome Miles G. Morales (voice)
Theresa Bentz Thanks
Phil Lord Producer, Writer, Additional Voices (voice)
Avi Arad Producer
Ziggy Marley Lenny (voice)
Juan Pope Additional Voices (voice)
Christopher Miller Producer, Writer, Additional Voices (voice)
Mònica Eggert Roig Animation
Quentin Marsollier Matte Painter
Bruce Tanis Sound Effects Editor
Ian McQue Other
Natasha Leonnet Digital Colorist
Nideep Varghese Animation
Sarah M. Sweeney Compositing Lead
Daniel Pemberton Original Music Composer
Lauren Sassen Story Artist
Peter Ramsey Executive Producer
Peter Sohn Ganke (voice)
Matt Dunkley Orchestrator, Conductor
Mary Hidalgo Casting
Dean Gordon Art Direction
Laide Agunbiade Lighting Artist, Compositing Artist
Ashley London Additional Voices (voice)
Dennis Singletary Additional Voices (voice)
Sitara Attaie Additional Voices (voice)