J.K. Simmons J. Jonah Jameson (voice)
Andrew Garfield Peter Parker / Spider-Man (archive footage) (uncredited)
Oscar Isaac Miguel O'Hara (voice)
Tobey Maguire Peter Parker / Spider-Man (archive footage) (uncredited)
Mahershala Ali Uncle Aaron (voice)
Hailee Steinfeld Gwen Stacy (voice)
Shea Whigham George Stacy (voice)
Andy Samberg Ben Reilly (voice)
Jason Schwartzman Spot (voice)
Denis Leary George Stacy (archive footage) (uncredited)
Jack Quaid Peter Parker (voice)
Daniel Kaluuya Hobie Brown (voice)
Elizabeth Perkins May / Quippy Spider-Person (voice)
Jake Johnson Peter B. Parker (voice)
Kathryn Hahn Doc Ock (voice)
Phil Lord Additional Voices (voice), Producer, Writer
Ayo Edebiri Glory (voice)
Donald Glover Aaron Davis
Amandla Stenberg Margo Kess: Spider-Byte (voice)
Greta Lee LYLA (voice)
Cliff Robertson Uncle Ben (archive footage) (uncredited)
Christopher Miller Producer, Additional Voices (voice), Writer
Brian Tyree Henry Jeff Morales (voice)
Issa Rae Jessica Drew (voice)
Rachel Dratch Ms. Weber (voice)
Jorma Taccone Adriano Tumino / '67 (voice)
Luna Lauren Vélez Rio Morales (voice)
Yuri Lowenthal Insomniac Spider-Man (voice)
Karan Soni Pavitr Prabhakar (voice)
Shameik Moore Miles Morales (voice)
Kimiko Glenn Peni Parker (voice) (uncredited)
Josh Keaton Spectacular Spider-Man (voice)
Peter Sohn Ganke (voice)
Amy Pascal Producer
Peggy Lu Mrs. Chen (uncredited)
Jharrel Jerome Miles G. Morales (voice)
Becky G Songs
A$AP Rocky Songs
Taran Killam Web-Slinger (voice)
David Callaham Writer
Daniel Pemberton Original Music Composer
Chrystee Pharris Additional Voices (voice)
Kimberly Bailey Additional Voices (voice)
Atsuko Okatsuka Yuri (voice)
Bob Persichetti Executive Producer
Kemp Powers Director
Hasan Minhaj Thanks
Jacqueline Pinol Additional Voices (voice)
Ziggy Marley Lenny (voice)
Peter Ramsey Executive Producer
Avi Arad Producer
Metro Boomin Songs, Metro Spider-Man (voice), Executive Music Producer
Rodney Rothman Executive Producer
Lex Lang Additional Voices (voice)
Joaquim Dos Santos Director
Dominic Fike Songs
Sofia Barclay Malala Windsor: Spider-UK (voice)
Andrea Navedo Additional Voices (voice)
Caitlin McKenna ADR Voice Casting, Additional Voices (voice)
June Christopher Additional Voices (voice)
Mary Hidalgo Casting
Reggie Yates Production Consultant
Mike Rianda Production Consultant, Additional Voices (voice)
Pierre Perifel Animation
Andrew Morgado Additional Voices (voice)
Shakira Ja'nai Paye Additional Voices (voice)
Melissa Sturm Mary Jane (voice)
Rez Kempton Additional Voices (voice)
Michael Semanick Sound Re-Recording Mixer
Al Rodrigo Additional Voices (voice)
Michelle Ruff Additional Voices (voice)
Offset Songs