Willem Dafoe Green Goblin / Norman Osborn
Kirsten Dunst Mary Jane Watson
J.K. Simmons J. Jonah Jameson
James Franco Harry Osborn
Tobey Maguire Spider-Man / Peter Parker
Emily Deschanel Receptionist
Joel McHale Mr. Jacks
Stan Lee Man Dodging Debris, Executive Producer, Comic Book
Elizabeth Banks Miss Brant
Brianna Brown Train Passenger
Alfred Molina Doc Ock / Otto Octavius
Bruce Campbell Snooty Usher
Reed Diamond 'Algernon'
Cliff Robertson Ben Parker
Daniel Dae Kim Raymond
Mageina Tovah Ursula
John Landis Doctor
Sam Raimi Director, University Student with Bag (uncredited)
Danny Elfman Original Music Composer
Joey Diaz Train Passenger
Rosemary Harris May Parker
Phil LaMarr Train Passenger (uncredited)
Dylan Baker Dr. Curt Connors
Marc John Jefferies Amazed Kid
Bill Nunn Joseph 'Robbie' Robertson
Ted Raimi Hoffman
Donna Murphy Rosalie Octavius
Daniel Gillies John Jameson
Vanessa Ferlito Louise
Elya Baskin Mr. Ditkovitch
Aasif Mandvi Mr. Aziz
Kevin Feige Executive Producer
Dion Lam Fight Choreographer
Joy Bryant Woman at Web
Scott Stokdyk Visual Effects Supervisor
Alvin Sargent Screenplay
Kyle Cooper Title Designer
Hal Sparks Elevator Passenger
Cindy Cheung Chinese Daughter (uncredited)
John Cameron Man Buying 'Spider-Man No More' Newspaper (uncredited)
Christine Estabrook Mrs. Jameson
Louis Lombardi Poker Player
Bonnie Somerville Screaming Woman (uncredited)
Alfred Gough Screenstory
Tony Campisi Train Passenger
Brent Briscoe Garbage Man
Kevin O'Connell Sound Re-Recording Mixer
Kelly Connell Dr. Isaacs
Miles Millar Screenstory
Howard London ADR Mixer
Peter McRobbie OsCorp Representative
Joseph M. Caracciolo Jr. Executive Producer
Steve Ditko Comic Book
Dan Hicks Train Passenger
Joseph M. Caracciolo Executive Producer, Priest at Mary Jane's Wedding (uncredited)
Michael Chabon Screenstory
Bill Pope Director of Photography
François Audouy Graphic Designer
Patricia M. Peters Screaming Nurse
Elyse Dinh Violinist
Alison Fisher Dialogue Editor
Peter Allas Train Passenger
Andre M. Johnson Fireman 2 (uncredited)
Molly Cheek Society Woman
Chad Stahelski Stunts
Steve Bartek Orchestrator, Additional Music
Diana R. Lupo Stunts
Neil Spisak Production Design
Christopher Flick Foley Supervisor
James Acheson Costume Design
Grant Anderson Sequence Lead
Avi Arad Producer