Peyton List Little Girl Playing on Steps (uncredited)
Elizabeth Banks Miss Brant
Willem Dafoe Green Goblin / Norman Osborn
James Franco Harry Osborn
Ted Raimi Hoffman
Dylan Baker Dr. Curt Connors
Emily Deschanel Receptionist
Kirsten Dunst Mary Jane Watson
Ilya Baskin Mr. Ditkovitch
J.K. Simmons J. Jonah Jameson
Tobey Maguire Spider-Man / Peter Parker
Molly Cheek Society Woman
Joel McHale Mr. Jacks
Brianna Brown Train Passenger
Stan Lee Man Dodging Debris, Executive Producer, Comic Book
Sam Raimi University Student with Bag (uncredited), Director
Brent Briscoe Garbage Man
Mageina Tovah Ursula
Christine Estabrook Mrs. Jameson
Daniel Gillies John Jameson
Alfred Molina Doc Ock / Otto Octavius
Avi Arad Producer
Bruce Campbell Snooty Usher
Aasif Mandvi Mr. Aziz
Tricia Linklater First Assistant Sound Editor
Daniel Dae Kim Raymond
Kevin Feige Executive Producer
Timothy Patrick Quill Train Passenger
Dan Hicks Train Passenger
Reed Diamond 'Algernon'
Chris O'Hara Stunts
Heather Sharpe Production Office Assistant
James Acheson Costume Design
Peter Allas Train Passenger
Phil LaMarr Train Passenger (uncredited)
Jeff Knipp Art Direction
Donna Murphy Rosalie Octavius
François Audouy Graphic Designer
Cliff Robertson Ben Parker
Dennis Sands Scoring Mixer
Adam Austin Set Dresser
Anthony Harris Digital Color Timer
H. Barclay Aaris Special Effects Technician
Bac DeLorme Second Assistant Director
Frank Bonsangue Pizza Man (uncredited)
Chad Stahelski Stunts
Vanessa Ferlito Louise
Joey Diaz Train Passenger
Andy Ryan Chief Lighting Technician
Garrett Warren Bearded Doctor (uncredited)
Joy Bryant Woman at Web
Bonnie Somerville Screaming Woman (uncredited)
John Paxton Houseman
Matt Blades Grip
Louis Lombardi Poker Player
Kirk Bloomberg Additional Second Assistant Camera
John Landis Doctor
David J. Grant Production Supervisor
Peter McRobbie OsCorp Representative
Jody Fedele Visual Effects Editor
Anne Betancourt Woman at Fire
Michael Chabon Screenstory
Danny Elfman Original Music Composer
Marc John Jefferies Amazed Kid
Joanne Baron Skeptical Scientist
Jason Hamer Special Effects
Eran Barnea Visual Effects
Alfred Gough Screenstory
Dion Lam Fight Choreographer
Steve Ditko Comic Book
Miles Millar Screenstory
Rosemary Harris May Parker