Kirsten Dunst Mary Jane Watson
Willem Dafoe Green Goblin / Norman Osborn
J.K. Simmons J. Jonah Jameson
Tobey Maguire Spider-Man / Peter Parker
James Franco Harry Osborn
Daniel Dae Kim Raymond
Alfred Molina Doc Ock / Otto Octavius
Sam Raimi Director, University Student with Bag (uncredited)
Emily Deschanel Receptionist
Elizabeth Banks Miss Brant
Stan Lee Man Dodging Debris, Executive Producer, Comic Book
Brianna Brown Train Passenger
Bruce Campbell Snooty Usher
Joel McHale Mr. Jacks
Kevin Feige Executive Producer
Dylan Baker Dr. Curt Connors
Cliff Robertson Ben Parker
Daniel Gillies John Jameson
Mageina Tovah Ursula
Elya Baskin Mr. Ditkovitch
Phil LaMarr Train Passenger (uncredited)
Aasif Mandvi Mr. Aziz
Rosemary Harris May Parker
Chad Stahelski Stunts
Danny Elfman Original Music Composer
Reed Diamond 'Algernon'
Noriko Watanabe Hairstylist
John Landis Doctor
Peter McRobbie OsCorp Representative
Chris O'Hara Stunts
Vanessa Ferlito Louise
John Cameron Man Buying 'Spider-Man No More' Newspaper (uncredited)
Steve Ditko Comic Book
Donna Murphy Rosalie Octavius
Louis Lombardi Poker Player
Ted Raimi Hoffman
Scott Spiegel Man on Balcony
Bonnie Somerville Screaming Woman (uncredited)
Joy Bryant Woman at Web
Molly Cheek Society Woman
Marc John Jefferies Amazed Kid
Hal Sparks Elevator Passenger
Alfred Gough Screenstory
Joanne Baron Skeptical Scientist
Miles Millar Screenstory
Dan Bradley Stunt Coordinator, Second Unit Director
Anne Betancourt Woman at Fire
Robert Alonzo Stunts
Tony Campisi Train Passenger
Alvin Sargent Screenplay
Garrett Warren Bearded Doctor (uncredited)
Hank Amos Stunts, Utility Stunts
Brent Briscoe Garbage Man
Timothy Patrick Quill Train Passenger
Bill Nunn Joseph 'Robbie' Robertson
Bill Calvert Train Passenger
Dion Lam Fight Choreographer
Avi Arad Producer
Brendan Patrick Connor Theater Traffic Cop
Donnell Rawlings Pizza "Heist" Witness
Lisa Hoyle Stunts
Christine Estabrook Mrs. Jameson
Bill Pope Director of Photography
Scott Stokdyk Visual Effects Supervisor
Diana R. Lupo Stunts
Jim Passon Color Timer
Kyle Cooper Title Designer
Jill Sayre Train Passenger
Joey Diaz Train Passenger
David Campbell Orchestrator
Gene LeBell Train Passenger (uncredited)
Kevin O'Connell Sound Re-Recording Mixer