J.K. Simmons J. Jonah Jameson
Willem Dafoe Green Goblin / Norman Osborn
Kirsten Dunst Mary Jane Watson
Bruce Campbell Snooty Usher
Tobey Maguire Spider-Man / Peter Parker
Alfred Molina Doc Ock / Otto Octavius
Stan Lee Man Dodging Debris, Executive Producer, Comic Book
James Franco Harry Osborn
Kevin Feige Executive Producer
Daniel Dae Kim Raymond
Dylan Baker Dr. Curt Connors
Elizabeth Banks Miss Brant
Sam Raimi Director, University Student with Bag (uncredited)
Rosemary Harris May Parker
Joel McHale Mr. Jacks
Brianna Brown Train Passenger
Emily Deschanel Receptionist
Cliff Robertson Ben Parker
Donna Murphy Rosalie Octavius
Reed Diamond 'Algernon'
Ted Raimi Hoffman
Chad Stahelski Stunts
Daniel Gillies John Jameson
Phil LaMarr Train Passenger (uncredited)
Vanessa Ferlito Louise
Michael Chabon Screenstory
Danny Elfman Original Music Composer
Aasif Mandvi Mr. Aziz
Bill Nunn Joseph 'Robbie' Robertson
Alfred Gough Screenstory
Steve Ditko Comic Book
John Landis Doctor
Miles Millar Screenstory
Bonnie Somerville Screaming Woman (uncredited)
Alvin Sargent Screenplay
Elya Baskin Mr. Ditkovitch
Avi Arad Producer
Chris O'Hara Stunts
Mageina Tovah Ursula
Molly Cheek Society Woman
Dion Lam Fight Choreographer
Peter McRobbie OsCorp Representative
Joey Diaz Train Passenger
Hal Sparks Elevator Passenger
John Cameron Man Buying 'Spider-Man No More' Newspaper (uncredited)
Joy Bryant Woman at Web
Christine Estabrook Mrs. Jameson
Donnell Rawlings Pizza "Heist" Witness
Scott Spiegel Man on Balcony
Louis Lombardi Poker Player
Diana R. Lupo Stunts
Hank Amos Stunts, Utility Stunts
Brent Briscoe Garbage Man
Gary Archer Prosthetics
Garrett Warren Bearded Doctor (uncredited)
Marc John Jefferies Amazed Kid
Gary Jones Costume Design
John Dykstra Visual Effects Designer
Anne Betancourt Woman at Fire
Kelly Connell Dr. Isaacs
Dan Bradley Stunt Coordinator, Second Unit Director
John Frazier Special Effects Supervisor
Tim Storms Chainsaw Doctor
Joanne Baron Skeptical Scientist
Dan Hicks Train Passenger
Roshon Fegan Amazed Kid
Kevin O'Connell Sound Re-Recording Mixer
Robert Alonzo Stunts
Cindy Cheung Chinese Daughter (uncredited)
Bill Calvert Train Passenger
Taylor Gilbert Mrs. Watson
Gene LeBell Train Passenger (uncredited)