Rose Byrne Helen Harris
Kristen Wiig Annie Walker, Screenplay, Co-Producer
Terry Crews Rodney
Melissa McCarthy Megan Price
Judd Apatow Producer
Jon Hamm Ted
Wendi McLendon-Covey Rita
Larry Kemp Dialogue Editor
Tim Heidecker Douglas Price
George H. Anderson Supervising Sound Editor
Clayton Townsend Producer
Tammy Fearing ADR Supervisor
Rebel Wilson Brynn
Casey Hotchkiss Camera Operator
Boni Yanagisawa Stunts
Maya Rudolph Lillian Donovan
Richard Riehle Bill Cozbi
Cindy Marty Sound Effects Editor
Heba Thorisdottir Makeup Department Head
Robert D. Yeoman Director of Photography
Matt Bennett Helen's Stepson
Chris O'Dowd Officer Rhodes
Jefferson Sage Production Design
Matt Lucas Gil
Jillian Bell Girl at Shower
Paul Feig Wedding Guest (uncredited), Director, Executive Producer
Olivia Summers Stunt Driver, Stunts
Dana Powell Flight Attendant Claire
Ellie Kemper Becca
William Kerr Editor
Jill Clayburgh Judy Walker
Jessica St. Clair Whitney
Chynna Phillips Chynna Phillips
Darrin Prescott Stunts
Ben Falcone Air Marshall Jon
Andy Buckley Helen's Husband
William Streit Electrician
Michael Hitchcock Don Cholodecki
Barry Mendel Producer
Don White Foley Mixer
Annie Mumolo Nervous Woman on Plane, Screenplay, Co-Producer
Greg Tuculescu Kevin
Jessie Graff Stunts
Janene Carleton Stunts
Joe Nuñez Oscar
Kali Hawk Kahlua
Suzanne LaChasse Hostess (uncredited)
Greg Zimmerman ADR Recordist
David Danon Key Hair Stylist
Marc Fishman Sound Re-Recording Mixer
Allison Jones Casting
Steve Arnold Set Designer
Lynne Marie Stewart Mrs. Donovan
Tom Yi Jewelry Store Couple
Leesa Evans Costume Design
Franklyn Ajaye Mr. Donovan
Chris Haarhoff Steadicam Operator, Camera Operator
Keith P. Cunningham Art Direction
Veronica Lorenz Makeup Artist
Nancy Carell Helen's Tennis Partner
Brian Petsos Pete
Sheila Waldron Script Supervisor
Goro Koyama Foley Artist
Adam Jenkins Sound Re-Recording Mixer
Greg Steele ADR Mixer
Michael Andrews Original Music Composer
Mitch Silpa Flight Attendant Steve
Jack Heeren Foley Mixer
Mia Rose Frampton Jewelry Store Girl
Jose Zamora Hairstylist
Jonathan Karp Music Supervisor
James Matheny Dialogue Editor