Kirsten Dunst Mary Jane Watson
Willem Dafoe Green Goblin / Norman Osborn
J.K. Simmons J. Jonah Jameson
James Franco Harry Osborn
Tobey Maguire Spider-Man / Peter Parker
Bill Hader Production Assistant
Stan Lee Comic Book, Man in Fair (uncredited), Executive Producer
Elizabeth Banks Miss Brant
Lucy Lawless Punk Rock Girl
Bruce Campbell Ring Announcer
Joe Manganiello Flash Thompson
Tony Ching Siu-Tung Stunt Coordinator
Cliff Robertson Ben Parker
Sam Raimi Director, Popcorn Thrower (uncredited)
Danny Elfman Original Music Composer
Octavia Spencer Check-In Girl
Rosemary Harris May Parker
Bill Nunn Joseph 'Robbie' Robertson
Ted Raimi Hoffman
Chris Coppola Kyle (uncredited)
David Koepp Screenplay
Sara Ramirez Cop at Carjacking
Gerry Becker Maximilian Fargas
Kevin Feige Production Executive
Stanley Anderson General Slocum
Una Damon Lab Tour Guide (uncredited)
Scott Stokdyk Visual Effects Supervisor
Joseph D'Onofrio Opinionated Cop
K.K. Dodds Simkins
George P. Wilbur Stunts
Francine Maisler Casting
Mike Smith Stunts
Al Goto Stunts, Cop (uncredited)
Jim Ward Project Coordinator
Peter Appel Cabbie
Kevin O'Connell Sound Re-Recording Mixer
Jack Betts Henry Balkan
Jim Passon Color Timer
Benny Urquidez Mugger (uncredited)
Tim DeZarn Philip Watson
Steve Ditko Comic Book
Larry Joshua Wrestling Promoter
Jesse Heiman Spectator at School Fight (uncredited)
Deborah La Mia Denaver Makeup Department Head
Jayce Bartok Subway Guitarist
François Audouy Assistant Art Director
Jophery C. Brown Chef (uncredited)
Mark Andrews Storyboard Artist
Ron Perkins Dr. Mendel Stromm
Rick Avery Cop (uncredited), Stunts
Spice Williams-Crosby Stunts
Paul Wurtzel Special Effects Technician
Alison Fisher ADR Editor
Sylva Kelegian Mother at Fire
Loren Janes Board of Directors Member (uncredited)
Tristan Paris Bourne Set Dresser
Annie Ellis Stunt Double
Deborah Wakeham Billy's Mom
Lisa Tomczeszyn Assistant Costume Designer
Scott L. Schwartz Screaming Wrestler (uncredited)
Neil Spisak Production Design
Macy Gray Macy Gray
Ajay Mehta Cabbie
James Acheson Costume Design
Brian J. Williams Young Thug #2 (uncredited)
Tom Boyd Musician
Avi Arad Executive Producer
Laura Ziskin Producer
Jim Norton Surly Truck Driver
John Dykstra Visual Effects Designer
Mark De Alessandro Stunts, Cop (uncredited)
Randy Poffo Bone Saw McGraw