Kirsten Dunst Mary Jane Watson
Robert Kerman Tugboat Captain
Willem Dafoe Green Goblin / Norman Osborn
J.K. Simmons J. Jonah Jameson
Ted Raimi Hoffman
James Franco Harry Osborn
Tobey Maguire Spider-Man / Peter Parker
Lucy Lawless Punk Rock Girl
Stan Lee Man in Fair (uncredited), Executive Producer, Comic Book
Elizabeth Banks Miss Brant
Bill Hader Production Assistant
Brad Grunberg Heckler
Bruce Campbell Ring Announcer
Chris Coppola Kyle (uncredited)
Jophery C. Brown Chef (uncredited)
Joe Manganiello Flash Thompson
Octavia Spencer Check-In Girl
Gerry Becker Maximilian Fargas
Joseph D'Onofrio Opinionated Cop
Timothy Patrick Quill Wrestling Arena Guard
Sam Raimi Director, Popcorn Thrower (uncredited)
Andray Johnson Balkan's Aide (uncredited)
James Acheson Costume Design
Jacquie Barnbrook Visual Effects Producer
Sylva Kelegian Mother at Fire
Martin Pfefferkorn Thug on 8x10 (uncredited)
Shan Omar Huey Teacher
Brian Ruberg Foley Mixer
François Audouy Assistant Art Director
Cliff Robertson Ben Parker
K.K. Dodds Simkins
Anthony Harris Digital Color Timer
Kevin Feige Production Executive
Danny Elfman Original Music Composer
Dion Hatch Digital Supervisor
Alyssa Fong Visual Effects
Evan Arnold Doctor
John Paxton Houseman
Matthew Dettmann Foley Artist
Ozzy Inguanzo Art Department Coordinator
Craig 'Radio Man' Castaldo Man with Bike (uncredited)
Jody Fedele Assistant Editor
Don Burgess Director of Photography
Jack Betts Henry Balkan
Macy Gray Macy Gray
Jim Ward Project Coordinator
Larry Joshua Wrestling Promoter
Tony Arnaud Grip
David Koepp Screenplay
Avi Arad Executive Producer
Laura Albert Stunts
James Marbas Digital Effects Supervisor
Mitch Goldstrom Systems Administrators & Support
Rosemary Harris May Parker
Michael Papajohn Carjacker
Randy Poffo Bone Saw McGraw
Sara Ramirez Cop at Carjacking
Cheli Clayton Second Assistant Camera
Peter Appel Cabbie
John Fedynich Location Manager
Mike Smith Stunts
Jon J. Bush Leadman
Benny Urquidez Mugger (uncredited)
Una Damon Lab Tour Guide (uncredited)
Tony Ching Siu-Tung Stunt Coordinator
Robert E. Denne Standby Painter
Tim DeZarn Philip Watson
Ray Scalice General Manager
Kristen Marie Holly Young Lady at Fire
Alan Frazier Assistant Chief Lighting Technician
Loren Janes Board of Directors Member (uncredited)
Jayce Bartok Subway Guitarist