Robert Kerman Tugboat Captain
Elizabeth Banks Miss Brant
Willem Dafoe Green Goblin / Norman Osborn
James Franco Harry Osborn
Ted Raimi Hoffman
Kirsten Dunst Mary Jane Watson
J.K. Simmons J. Jonah Jameson
Tobey Maguire Spider-Man / Peter Parker
Lucy Lawless Punk Rock Girl
Octavia Spencer Check-In Girl
Jesse Heiman Spectator at School Fight (uncredited)
Stan Lee Man in Fair (uncredited), Executive Producer, Comic Book
Sam Raimi Popcorn Thrower (uncredited), Director
Brad Grunberg Heckler
Tim DeZarn Philip Watson
Chris Coppola Kyle (uncredited)
Avi Arad Executive Producer
Bruce Campbell Ring Announcer
Jophery C. Brown Chef (uncredited)
Bill Hader Production Assistant
Joe Manganiello Flash Thompson
Jon J. Bush Leadman
Gerry Becker Maximilian Fargas
Joseph D'Onofrio Opinionated Cop
Kevin Feige Production Executive
Timothy Patrick Quill Wrestling Arena Guard
Andray Johnson Balkan's Aide (uncredited)
James Acheson Costume Design
Jacquie Barnbrook Visual Effects Producer
Sylva Kelegian Mother at Fire
Shan Omar Huey Teacher
Brian Ruberg Foley Mixer
François Audouy Assistant Art Director
Cliff Robertson Ben Parker
Bill Díaz Lead Animator
K.K. Dodds Simkins
Anthony Harris Digital Color Timer
Myk Watford Cop at Fire
Don Burgess Director of Photography
Alan Frazier Assistant Chief Lighting Technician
Dion Hatch Digital Supervisor
Alyssa Fong Visual Effects
Evan Arnold Doctor
John Paxton Houseman
Matthew Dettmann Foley Artist
Ozzy Inguanzo Art Department Coordinator
Jody Fedele Assistant Editor
Martin Pfefferkorn Thug on 8x10 (uncredited)
Michael Papajohn Carjacker
Jack Betts Henry Balkan
Danny Elfman Original Music Composer
Lloyd Lee Barnett Digital Compositors
Ron Perkins Dr. Mendel Stromm
Zigmund Gron Music Editor
Larry Joshua Wrestling Promoter
Tony Arnaud Grip
James Marbas Digital Effects Supervisor
Steve Ditko Comic Book
Mitch Goldstrom Systems Administrators & Support
Rosemary Harris May Parker
Randy Poffo Bone Saw McGraw
Sara Ramirez Cop at Carjacking
Peter Brown Sound Effects Editor
Cheli Clayton Second Assistant Camera
Peter Appel Cabbie
John Fedynich Location Manager
Mike Smith Stunts
Benny Urquidez Mugger (uncredited)
Una Damon Lab Tour Guide (uncredited)
Tony Ching Siu-Tung Stunt Coordinator
Robert E. Denne Standby Painter
Ray Scalice General Manager