Renée Zellweger Vanessa Bloome (voice)
Patrick Warburton Ken (voice)
Sting Sting (voice)
Tress MacNeille Jeanette Chung / Mother / Cow (voice)
John DiMaggio Janitor / Bailiff (voice)
David Herman Buzz / Bob Bumble / Pilot (voice)
Matthew Broderick Adam Flayman (voice)
Kathy Bates Janet Benson (voice)
Ray Liotta Ray Liotta (voice)
John Goodman Layton T. Montgomery (voice)
Chris Rock Mooseblood (voice)
Hans Zimmer Executive Music Producer
Michael Richards Bud Ditchwater (voice)
Larry King Bee Larry King (voice)
Barry Levinson Martin Benson (voice)
Rip Torn Lou Lo Duca (voice)
Conrad Vernon Freddy (voice)
Jim Cummings Narrator / Graduation Announcer (voice)
Larry Miller Buzzwell (voice)
Megan Mullally Trudy (voice)
Jennifer Kluska Storyboard Artist
Oprah Winfrey Judge Bumbleton (voice)
Andy Nelson Sound Mixer
Anna Behlmer Sound Mixer
Jerry Seinfeld Producer, Barry B. Benson (voice), Writer
Randy Thom Sound Designer
Frank Rinella Foley Mixer
Thomas J. O'Connell ADR Mixer
David C. Lawson Director of Photography
Matt Patterson Sound Recordist
Carol Leifer Press Person #1 (voice)
Kyrsten Mate Sound Effects Editor
David G. Derrick Jr. Story Artist
Steve Cunningham Animation
Tom Papa Splitz / Klauss Vanderhayden (voice)
Brian Hopkins Sandy Shrimpkin / TSA Agent (voice)
Gabe Hordos Art Department Coordinator
Simon Otto Animation
Simon J. Smith Director, Truck Driver / Chet (voice)
Spike Feresten Writer
Steve Hickner Director
Will Files Supervising Sound Editor, Sound Designer
Andy Robin Jock #2 (voice), Writer
Christi Soper Hilt Casting Associate
Mo Henry Negative Cutter
Dennie Thorpe Foley Artist
Mario Joyner Jackson (voice)
Jeff Altman Uncle Carl (voice)
Rupert Gregson-Williams Music
Leigh French ADR Voice Casting
David Yanover Post Production Supervisor
Blake R. Cornett Sound Recordist
Ellen Heuer Foley Artist
Barry Marder Waterbug (voice), Writer
Alan Meyerson Scoring Mixer
Sean Bishop Ladybug (voice)
Steve Slanec ADR Editor
Alex McDowell Production Design
Scott Guitteau Sound Effects Editor
Christina Steinberg Producer
Leslee Feldman Casting
Jana Vance Foley Artist
Sean England Foley Recordist
Luke Dunn Gielmuda Foley Supervisor
Mark Swift Co-Producer
Kevin Andrus Animation
J.J. George Music Editor
Chris Bancroft Animation
Nick Fletcher Editor
Wayne Hellinger Post Production Coordinator
Terry Claborn Color Timer
Seth Engstrom Conceptual Design