Emma Thompson Karen
Thomas Brodie-Sangster Sam
Elisha Cuthbert Carol-Anne, American Goddess
Chiwetel Ejiofor Peter
Liam Neeson Daniel
Hugh Grant The Prime Minister
Keira Knightley Juliet
Colin Firth Jamie Bennett
Denise Richards Carla, the Real Friendly One
Billy Bob Thornton The US President
Rowan Atkinson Rufus, Jewellery Salesman
Bill Nighy Billy Mack
Ivana Miličević Stacey, American Dreamgirl
Martin Freeman John
Rodrigo Santoro Karl
Alan Rickman Harry
Frances de la Tour Lesbian Lover (uncredited)
Laura Linney Sarah
Kris Marshall Colin Frissell
Emma Buckley Jamie's Sister
Sienna Guillory Jamie's Girlfriend
Shannon Elizabeth Harriet, the Sexy One
Andrew Lincoln Mark
January Jones Jeannie, American Angel
Adam Godley Mr Trench
Anne Reid Headmistress (uncredited)
Perry Montague Mason Orchestrator
Heike Makatsch Mia
Richard Curtis Trombone Player (uncredited), Screenplay, Director
Jeanne Moreau Taxi Passenger at Marseille Airport (uncredited)
Lúcia Moniz Aurelia
Andrew Findon Musician
Matt Dunkley Orchestrator
Nina Sosanya Annie
Eric Fellner Producer
Julia Davis Nancy the Caterer
Olivia Olson Joanna Anderson
Meg Wynn Owen PM's Secretary
Peter N. Brown Supervising Carpenter
Mary Selway Casting
Tim Bevan Producer
Nick Watson Dolby Consultant
Arnaud Duterque Location Manager
George Cottle Stunt Double
Margery Mason Harris Street Old Lady
Claudia Schiffer Carol
John Sharian Wisconsin Taxi Driver
Martine McCutcheon Natalie
Edward Hardwicke Sam's Grandfather
Wayne Leach Best Boy Electric
Gregor Fisher Joe
Paul Heasman Airport Guard
Joanna Page Just Judy
Fiona Weir Casting
Jamie Edgell Airport Guard
Declan Donnelly Dec
Debra Hayward Co-Producer
Mark Berrow Musician
Joanna Johnston Costume Design
Anthony McPartlin Ant
Brian Bovell Radio Watford DJ
Elisabeth Margoni Eleonore
Glenn Freemantle Sound Supervisor
Bill Moody Natalie's Dad
Liza Chasin Co-Producer
Deborah Harding Post Production Supervisor
Rory MacGregor Engineer
Abdul Salis Tony
Peter Marinker US Expert
Gillian Barge Cabinet Minister
Christopher Newman First Assistant Director
Alexandra Hill Music Coordinator