Dax Shepard Self (uncredited)
Jessica Alba Self (uncredited)
Seth Rogen Ben Stone, Executive Producer
Paul Rudd Pete
Andy Dick Self (uncredited)
Steve Carell Self (uncredited)
James Franco Self (uncredited)
Alan Tudyk Jack
Leslie Mann Debbie
Joanna Kerns Alison's Mom
Catherine Reitman Alison's Friend
Kristen Wiig Jill
Bill Hader Brent
Eva Mendes Self (uncredited)
Jay Baruchel Jay
Adam Scott Samuel
Charlyne Yi Jodi
Martin Starr Martin
Katherine Heigl Alison Scott
Brianna Brown Alison's Friend
Mo Collins Female Doctor
Jonah Hill Jonah
Steven Brill Ben's Boss
Maude Apatow Sadie
Pauletta O. Lewis Hairstylist
Ana Mercedes Maria
Craig Robinson Club Doorman
B.J. Novak Young Doctor
Wayne Federman Fantasy Baseball Guy
Ken Jeong Dr. Kuni
Nautica Thorn Lap Dancer
Tami Sagher Wardrobe Lady
Nick Thune Alison's Friend
Marc Wostak Electrician
Eric Roberts Video Assist Operator
Wendy Hoffmann ADR Voice Casting
Harold Ramis Ben's Dad
Bill 'Kauhane' Hoyt Standby Painter
Lyle Workman Additional Music
Paul Feig Fantasy Baseball Guy
Terry Miller Construction Foreman
Chris Weigand Lighting Technician
Peter Geraghty Second Assistant Camera
Paul Tilden Second Assistant Camera
Colin Patton Assistant Editor
Evan Goldberg Executive Producer
Shauna Robertson Producer
Cherie Tamai First Assistant Sound Editor
Jason Segel Jason
Tim Bagley Dr. Pellagrino
Iris Apatow Charlotte
Alicia Maccarone Set Designer
Dawn Massaro Second Unit First Assistant Director
J.P. Manoux Dr. Angelo
Judd Apatow Director, Screenplay, Producer
Dorian Frankel Casting Assistant
Clayton Townsend Producer, Unit Production Manager
Jay M. Huntoon Video Assist Operator
Matthew McKane Club Bartender
Rebecca Asher Script Supervisor
Debra McGuire Costume Design
Jim Small Assistant Location Manager
Jimmy Fusil Digital Intermediate Producer
William Streit Lighting Technician
Gary Burritt Negative Cutter
Allison Jones Casting
Loudon Wainwright III Original Music Composer, Dr. Howard
Deedra Ricketts Extras Casting
Jesse Heiman Stand In
Glen Magers Electrician
Lisa Goldberg Producer's Assistant
Peter McKernan Jr. Pilot