Suzy Eddie Izzard Sir Miles Axlerod (voice)
Owen Wilson Lightning McQueen (voice)
Michael Caine Finn McMissile (voice)
Bonnie Hunt Sally (voice)
Jason Isaacs Siddeley / Leland Turbo (voice)
Edie McClurg Minny (voice)
Cheech Marin Ramone (voice)
Jenifer Lewis Flo (voice)
John Lasseter Additional Voices (voice), Director, Original Story
Emily Mortimer Holley Shiftwell (voice)
Tony Shalhoub Luigi (voice)
John Turturro Francesco Bernoulli (voice)
Katherine Helmond Lizzie (voice)
Vanessa Redgrave The Queen / Mama Topolino (voice)
Joe Mantegna Grem (voice)
Bruce Campbell Rod "Torque" Redline (voice)
Peter Jacobson Acer (voice)
Josh Cooley Storyboard Artist, Additional Script Supervisor
Lewis Hamilton Lewis Hamilton (voice)
Franco Nero Uncle Topolino (voice)
Jeff Gordon Jeff Gorvette (voice)
Scott Morse Storyboard Artist
Daniel Chong Storyboard Artist
Richard Kind Van (voice)
John Ratzenberger Mack (voice)
Michael Giacchino Original Music Composer
Thomas Kretschmann Professor Z (voice)
Stanley Townsend Victor Hugo / Vladimir Trunkov / Ivan the Tow Truck (voice)
Dan Fogelman Original Story
Robbie Williams Songs
Jeff Garlin Otis (voice)
Gary Rydstrom Thanks
Paul Dooley Sarge (voice)
John Mainieri J. Curby Gremlin (voice)
Steve Jobs Thanks
Larry the Cable Guy Mater (voice)
Stephen L. Wong Animation
Velibor Topic Alexander Hugo (voice)
Ben Queen Screenplay
Zijad Gračić Flin McFin (uncredited)
Dennie Thorpe Foley Artist
Jerome Ranft Sculptor
Harley Jessup Production Design
Teresa Gallagher Mater's Computer (voice)
Tom Myers Sound Designer
George Doering Musician
Denise Ream Producer
Guido Quaroni Guido (voice)
Jana Vance Foley Artist
Sig Hansen Crabby (voice)
Lauren Montuori Production Coordinator
Alma Prica Helena Hitrosift (uncredited)
Michael Sauls Fix Animator
Raphael Suter Animation
Al Nelson Sound Effects Editor
Bradford Lewis Tubbs Pacer (voice), Original Story, Co-Director
Neil Helm Animation
Charu Clark Lighting Artist
Don Crum Animation
Andrea Datzman Orchestrator, Music Coordinator
Royce Wesley Animation
Catherine Hang-Hicks Animation
Holger Leihe Animation
Brett Schulz Animation
James Thatcher Musician
Michael Rutter Set Dressing Artist
Bruce Kuei Animation
Simon Diggins ADR Recordist
Teresa Eckton Sound Effects Editor
Brent Musburger Brent Mustangburger (voice)
Andrew Page Music Director
Anna Noakes Musician