Lisa Kudrow Janice Templeton (voice)
James Marsden Tim Templeton (voice)
Jeff Goldblum Dr. Armstrong (voice)
David Soren Jimbo (voice)
Ariana Greenblatt Tabitha Templeton (voice)
Eva Longoria Carol Templeton (voice)
Amy Sedaris Tina Templeton (voice)
Hans Zimmer Original Music Composer
Alec Baldwin Theodore Templeton (voice)
David P. Smith Movie Patron (voice)
Steve Mazzaro Original Music Composer
James Ryan Story Bear (Connie) (voice)
Raphael Alejandro Nathan / Lead Baby Ninja (voice)
Jimmy Kimmel Ted Templeton (voice)
Reyn Doi Box Kid (voice)
Christi Soper Hilt Casting
Paul N.J. Ottosson Supervising Sound Editor, Sound Designer
Beau Borders Sound Re-Recording Mixer
Tom McGrath Director, Story, Dr. Tiffany Hamilton (voice)
Walt Dohrn Baby Bouncer (voice)
Andrew Harkins Animation
Michael McCullers Writer, Story, Characters
Jeff Hermann Producer
James Morioka Dialogue Editor
Raymond Zibach Production Design
Matt Yocum Sound Effects Editor
Lisa Curtis Saunders Pipeline Technical Director
April Lawrence Acorn Center Computer (voice)
Luke Schwarzweller Sound Mix Technician
Nelson Yokota Storyboard Artist
Mark A. Hester Editor
Michael J. Broomberg Foley Artist
Pedro Eustache Musician
Miles Bakshi Young Tim Voice-Over (voice)
Mary Blee Editor
Marla Frazee Producer, Novel
James McGrath Wizzie (voice)
Collin Erker Time Out Kid (voice)
Nova Reed Little Bo Peep Baby (voice)
Dave Needham Glue Baby (voice)
Angelo Raguso Sound Mixer
Christopher Gonzalez Animation
Serenity Reign Brown Meghan (voice)
Andy Schuhler Art Direction
Christian Schaanning Sound Effects Editor
Stephen Wood Special Effects
John Swanson Associate Producer
Marjorie Cohn Pageant Mom 2 (voice)
Nicholas Gist The Triplets (voice)
Ashlyn Lundahl 'No' Girl (voice)
Jon Eric Schmidt Associate Producer
Carl Roberts Foley Recordist
Molly K. Gray Creepy Girl (voice)
Christopher Brock Art Direction
Connor Albrecht Dreidel Kid (voice)
Kristin Lowe Pageant Mom 1 (voice)