Johnny Depp Rango / Lars (voice)
Timothy Olyphant Spirit of the West (voice)
Bill Nighy Rattlesnake Jake (voice)
Ryan Hurst Jedidiah (voice)
Abigail Breslin Priscilla (voice)
Alfred Molina Roadkill (voice)
Stephen Root Doc / Merrimack / Mr. Snuggles (voice)
Isla Fisher Beans (voice)
Gore Verbinski Producer, Story, Director, Sgt Turley / Crevice / Slim / Lupe - Mariachi Violin (voice)
Hans Zimmer Original Music Composer
Alanna Ubach Boo / Cletus / Fresca / Miss Daisy (voice)
Ray Winstone Bad Bill (voice)
Gil Birmingham Wounded Bird (voice)
Beth Grant Bonnie (voice)
Claudia Black Angelique (voice)
John Logan Writer, Story
Harry Dean Stanton Balthazar (voice)
Maile Flanagan Lucky (voice)
Vincent Kartheiser Ezekiel / Lasso Rodent (voice)
Ian Abercrombie Ambrose (voice)
John Cothran Elgin (voice)
Ned Beatty Mayor (voice)
Graham King Producer
Blake Clark Buford (voice)
Jessica Drake Dialect Coach
Joe Nuñez Rock-Eye (voice)
Denise Chamian Casting
Keith Campbell Sod Buster (voice), Stunt Coordinator
Christopher Boyes Sound Re-Recording Mixer
Kym Whitley Melonee (voice)
Jim Passon Color Timer
Charles Fleischer Elbows (voice)
Lew Temple Furgus / Hitch (voice)
Lorne Balfe Additional Music
Hemky Madera Chorizo (voice)
Roger Deakins Director of Photography
Michael Silvers Supervising Dialogue Editor
Tim Headington Executive Producer
Patrika Darbo Delilah / Maybelle (voice)
Adam Somner First Assistant Director, Production Manager
Alex Manugian Spoons (voice)
Paul Massey Sound Re-Recording Mixer
John Knoll Visual Effects Supervisor
Kevin Kaska Orchestrator
Nick Glennie-Smith Conductor
Tiến Nguyễn Production Assistant
Shannon Mills Sound Effects Editor
Doc Kane ADR Mixer
Dennie Thorpe Foley Artist
George Doering Musician
George DelHoyo Señor Flan - Mariachi Accordion (voice)
Todd Vaziri Compositing Lead
Lee Orloff Sound Mixer
James Ward Byrkit Head of Story, Storyboard Artist, Story, Waffles / Gordy / Papa Joad / Cousin Murt / Curlie / Knife Attacker / Rodent Kid (voice)
Christopher Lee Parson Hazel / Kinski / Stump / Clinker / Lenny / Boseefus (voice)
David C. Hughes Sound Effects Editor
Dominic Lewis Additional Music
David Feiss Story Artist
Ruth Lambert Additional Casting
Dee Selby Foley Editor
Arturo Sandoval Musician
Hal Hickel Animation Supervisor, Animation Director
Steve Slanec Foley Supervisor
Adam Kopald Sound Editor
Holly Dorff ADR Voice Casting
Martin Schaer Camera Operator
John Bartnicki Production Assistant
Addison Teague Supervising Sound Editor, Sound Designer
J.R. Grubbs Sound Effects Editor
Jana Vance Foley Artist
Heitor Pereira Additional Music, Musician
Frank Rinella Foley Mixer