Isla Fisher Beans (voice)
Johnny Depp Rango / Lars (voice)
Bill Nighy Rattlesnake Jake (voice)
Timothy Olyphant Spirit of the West (voice)
Abigail Breslin Priscilla (voice)
Jessica Drake Dialect Coach
Alfred Molina Roadkill (voice)
Stephen Root Doc / Merrimack / Mr. Snuggles (voice)
Ryan Hurst Jedidiah (voice)
Ray Winstone Bad Bill (voice)
Patrika Darbo Delilah / Maybelle (voice)
Arturo Sandoval Musician
Hans Zimmer Original Music Composer
Maile Flanagan Lucky (voice)
Hemky Madera Chorizo (voice)
Alanna Ubach Boo / Cletus / Fresca / Miss Daisy (voice)
Marco Foglia Animation
Vincent Kartheiser Ezekiel / Lasso Rodent (voice)
Claudia Black Angelique (voice)
Gore Verbinski Director, Story, Producer, Sgt Turley / Crevice / Slim / Lupe - Mariachi Violin (voice)
Gil Birmingham Wounded Bird (voice)
John Logan Writer, Story
Michael Lum Animation
Robert McGee Additional Casting
Martin Schaer Camera Operator
Peter Geraghty First Assistant "B" Camera
Harry Dean Stanton Balthazar (voice)
Beth Grant Bonnie (voice)
Ned Beatty Mayor (voice)
Charles Fleischer Elbows (voice)
Peter G. Adams Musician
Blake Clark Buford (voice)
Lew Temple Furgus / Hitch (voice)
Mike Marcuzzi Creature Technical Director
Christopher Lee Parson Hazel / Kinski / Stump / Clinker / Lenny / Boseefus (voice)
Jacqui Lopez Visual Effects Producer
Frank Rinella Foley Mixer
Keith Campbell Sod Buster (voice), Stunt Coordinator
Kym Whitley Melonee (voice)
Denise Chamian Casting
Ian Abercrombie Ambrose (voice)
Jen Howard Compositing Lead
Phill Boucher Score Engineer
Cristin Pescosolido Compositor
Adam Kopald Sound Editor
Patrick Hoeschen Gaffer
Roger Deakins Director of Photography
John Cothran Elgin (voice)
Lorne Balfe Additional Music
George DelHoyo Señor Flan - Mariachi Accordion (voice)
Christopher Boyes Sound Re-Recording Mixer
Heitor Pereira Musician, Additional Music
Coya Elliott Assistant Dialogue Editor
Todd Vaziri Compositing Lead
Joe Nuñez Rock-Eye (voice)
Raul Essig CG Supervisor
James Ward Byrkit Story, Waffles / Gordy / Papa Joad / Cousin Murt / Curlie / Knife Attacker / Rodent Kid (voice), Storyboard Artist, Head of Story
Hal Hickel Animation Director, Animation Supervisor
Chuck Duke Animation
Adam Somner Production Manager, First Assistant Director
Graham King Producer
Holly Dorff ADR Voice Casting
Erik Morgansen Animation
George Doering Musician
Florian Witzel Visual Effects Technical Director
Jim Passon Color Timer
James Goldman Assistant Camera
Leandro Estebecorena CG Supervisor
Beauxregard Neylon ADR Mixer
David Feiss Story Artist
Dennie Thorpe Foley Artist
Jeff Grebe Sequence Supervisor