Johnny Depp Rango / Lars (voice)
Timothy Olyphant Spirit of the West (voice)
Stephen Root Doc / Merrimack / Mr. Snuggles (voice)
Abigail Breslin Priscilla (voice)
Isla Fisher Beans (voice)
Hans Zimmer Original Music Composer
Bill Nighy Rattlesnake Jake (voice)
Ray Winstone Bad Bill (voice)
Alfred Molina Roadkill (voice)
Alanna Ubach Boo / Cletus / Fresca / Miss Daisy (voice)
Vincent Kartheiser Ezekiel / Lasso Rodent (voice)
Harry Dean Stanton Balthazar (voice)
Claudia Black Angelique (voice)
Ryan Hurst Jedidiah (voice)
Gil Birmingham Wounded Bird (voice)
Beth Grant Bonnie (voice)
Kym Whitley Melonee (voice)
Gore Verbinski Producer, Story, Director, Sgt Turley / Crevice / Slim / Lupe - Mariachi Violin (voice)
John Logan Writer, Story
Ned Beatty Mayor (voice)
James Ward Byrkit Head of Story, Storyboard Artist, Story, Waffles / Gordy / Papa Joad / Cousin Murt / Curlie / Knife Attacker / Rodent Kid (voice), Character Designer
Blake Clark Buford (voice)
Hemky Madera Chorizo (voice)
Lew Temple Furgus / Hitch (voice)
Lorne Balfe Additional Music
Maile Flanagan Lucky (voice)
Steve Slanec Foley Supervisor
John Cothran Elgin (voice)
Roger Deakins Director of Photography
Joe Nuñez Rock-Eye (voice)
Patrika Darbo Delilah / Maybelle (voice)
Ian Abercrombie Ambrose (voice)
Jim Passon Color Timer
Nick Glennie-Smith Conductor
Geoff Zanelli Additional Music
Graham King Producer
Christopher Lee Parson Hazel / Kinski / Stump / Clinker / Lenny / Boseefus / Dirt Kid (voice)
Charles Fleischer Elbows (voice)
Keith Campbell Sod Buster (voice), Stunt Coordinator
Christopher Boyes Sound Re-Recording Mixer
David Feiss Story Artist
Adam Somner Production Manager, First Assistant Director
Ben O'Brien Digital Compositor
Jessica Drake Dialect Coach
Denise Chamian Casting
Kevin Kaska Orchestrator
George DelHoyo Señor Flan - Mariachi Accordion (voice)
Simon Morgan First Assistant Editor
Tim Headington Executive Producer
Tiến Nguyễn Production Assistant
Joe Murray Character Designer
Heitor Pereira Additional Music, Musician
Coya Elliott Assistant Dialogue Editor
Shannon Mills Sound Effects Editor
James Thatcher Musician
John Knoll Visual Effects Supervisor
Lee Orloff Sound Mixer
Dominic Lewis Additional Music
Addison Teague Supervising Sound Editor, Sound Designer
Paul Massey Sound Re-Recording Mixer
Michael Silvers Supervising Dialogue Editor
George Doering Musician
Jana Vance Foley Artist
Arturo Sandoval Musician
Ruth Lambert Additional Casting
James Goldman Assistant Camera
Martin Schaer Camera Operator
Dee Selby Foley Editor
Frank Rinella Foley Mixer
John Bartnicki Production Assistant
David Hidalgo Musician
Shawn Kelly Lead Animator