Jessie Buckley Queen Victoria
Robert Downey Jr. Dr. John Dolittle
Ralph Fiennes Barry (voice)
Tom Holland Jip (voice)
Jim Broadbent Lord Thomas Badgley
Rami Malek Chee-Chee (voice)
Emma Thompson Poly (voice)
John Cena Yoshi (voice)
Antonio Banderas King Rassouli
Steve Bartek Orchestrator
Selena Gomez Betsy (voice)
Jason Mantzoukas James the Dragonfly (voice)
Will Arnett Rabbit (voice) (uncredited)
Octavia Spencer Dab-Dab (voice)
Marion Cotillard Tutu (voice)
Kumail Nanjiani Plimpton (voice)
Malcolm McLean "C" Camera Operator
Michael Sheen Dr. Blair Müdfly
Emily Brockmann Casting Associate
Ralph Ineson Arnall Stubbins
Mark Umbers Lieutenant
Sid Sagar Jeff the Prisoner
Kasia Smutniak Lily Dolittle
Samson Kayo Pirate
Craig Robinson Kevin (voice)
Frances de la Tour Dragon (voice)
Lloyd Bass Stunts
Oleg Podobin Stunts
Sebastian Lochmann Concept Artist
Clive Francis Archbishop
Stewart Scudamore Pirate
Rob Cooper Stunts
Stacy Mann Unit Publicist
Brian Nickels Stunts
Douglas Robson Stunts
Danny Elfman Original Music Composer
Harry Collett Tommy Stubbins
Benjamin Ashley Stunts
Ranjani Brow Mouse (voice)
Martin Pemberton Postman, Stunts
Edgardo Simone Orchestrator
Alexander Bracq Stunts
Nick Moore Additional Editing
Susan Downey Producer
Sam Stefan Stunts
Kelly Stables Mouse (voice)
Matt King Clyde
Benjamin A. Burtt Sound Effects Editor
Scott Menville Army Ant (voice)
Tim Treloar Humphrey the Whale (voice)
Alison Clements Draughtsman
Katy Bullock Stunts
J.R. Grubbs Supervising Sound Editor
Lee Sandales Set Decoration
Martin Wilde Stunts
Matthew Stirling Stunts
Joanna Page Bethan Stubbins
Glenn Foster Stunts
Guillermo Navarro Director of Photography
Pete Anthony Orchestrator
Joe Kennard Stunts
Craig Alpert Editor
Frank Cuomo Production Manager
Julian Bucknall First Assistant Camera, First Assistant "A" Camera
Dan Gregor Screenplay
Daniel Phillips Makeup Designer, Hair Designer
Jenny Beavan Costume Design
Chris Munro Production Sound Mixer
Chris Pollard Stunts
Rachelle Beinart Stunt Double
Jon Taylor Sound Re-Recording Mixer
Lisa Rodgers Post Production Supervisor