Tom Holland Jip (voice)
Robert Downey Jr. Dr. John Dolittle
Marion Cotillard Tutu (voice)
John Cena Yoshi (voice)
Antonio Banderas King Rassouli
Jessie Buckley Queen Victoria
Jason Mantzoukas James the Dragonfly (voice)
Ralph Fiennes Barry (voice)
Will Arnett Rabbit (voice) (uncredited)
Ralph Ineson Arnall Stubbins
Emma Thompson Poly (voice)
Selena Gomez Betsy (voice)
Rami Malek Chee-Chee (voice)
Jim Broadbent Lord Thomas Badgley
Joanna Page Bethan Stubbins
Harry Collett Tommy Stubbins
Danny Elfman Original Music Composer
Octavia Spencer Dab-Dab (voice)
Michael Sheen Dr. Blair Müdfly
Frances de la Tour Dragon (voice)
Samson Kayo Pirate
Kumail Nanjiani Plimpton (voice)
Craig Robinson Kevin (voice)
Carmel Laniado Lady Rose
Kasia Smutniak Lily Dolittle
Stephen Gaghan Screenplay, Director
Sarah Bradshaw Unit Production Manager, Associate Producer
Mark Umbers Lieutenant
Oliver Chris Sir Gareth
Levan Doran Stunts
Scott Menville Army Ant (voice)
Hugh Lofting Characters, Character Designer
Dan Gregor Screenplay
Sonny Ashbourne Serkis Arnall Stubbins Jr.
Matt King Clyde
Clive Francis Archbishop
Kelly Stables Mouse (voice)
Joe Roth Producer
Stewart Scudamore Pirate
Peter Hayley-Barker Grip
Doug Mand Screenplay
Guillermo Navarro Director of Photography
Steve Bartek Orchestrator
John-Luke Roberts Pirate / Animal Performer
Lee Sandales Set Decoration
Erol Mehmet Stunts
Chris Lebenzon Editor
Susan Downey Producer
Joe Kennard Stunts
Nick Fisher Mini the Sugar Glider (voice)
Matt Sherren Stunts
Kelly Dent Stunts
Paula Price Makeup Artist
Elliot Barnes-Worrell Captain William Derrick
Jack Whittaker Sound Effects Editor
Lyndon S. Hellewell Stunts
Brian Nickels Stunts
William M. Connor Co-Producer, First Assistant Director
Martin Pemberton Stunts, Postman
Pier Lefebvre Digital Effects Supervisor
David Sheinkopf Don Carpenterino
Jacob Riehle Dialogue Editor
Sarah Young Assistant Costume Designer
Laura Dishington Graphic Designer
Lloyd Bass Stunts
Frazer Fennell-Ball Second Assistant Director
Richard Ruck Unit Manager
Bill Abbott Music Editor
Jeff Kirschenbaum Producer
Steve Jehu Stunts
Allison Paul Visual Effects Producer
Graham Sutton Music Editor