Anne Hathaway Maggie Murdock
Jake Gyllenhaal Jamie Randall
Katheryn Winnick "Lisa"
Judy Greer Cindy
Gabriel Macht Trey Hannigan
Conan O'Brien Self (archive footage) (uncredited)
Josh Gad Josh Randall
Jaimie Alexander Carol (uncredited)
Oliver Platt Bruce Winston
Hank Azaria Dr. Stan Knight
George Segal Dr. James Randall
James Newton Howard Original Music Composer
Jill Clayburgh Nancy Randall
Scott Cohen Ted Goldstein
Edward Zwick Producer, Screenplay, Director
Michael Chernus Jerry
Megan Ferguson Farrah
Michael Buffer Pfizer Convention MC
Ian Harding Pfizer Trainee #1
Andy Nelson Sound Re-Recording Mixer
Nikki DeLoach Christy
Peter Friedman California Man
Maximilian Osinski Ned
Kate Jennings Grant Gina
Frédéric North Pilot, Stunts
Peter Epstein Stunts
Charles Randolph Screenplay, Producer
Natalie Gold Dr. Helen Randall
Alan D'Angerio Hairstylist
Marshall Herskovitz Screenplay, Producer
Geneva Carr Viagra Nurse #2
Kimberly Scott Gail
Brian Hutchison Homeless Man
Arnon Milchan Executive Producer
Peter Swords King Makeup Artist
Larissa Emanuele Convention Girl #2
Victoria Thomas Casting
Maïté Schwartz Texas
Jay B. Richardson Music Editor
Sharon Wilkins La Boheme Receptionist
Stephen A. Pope Stunt Coordinator
Kate Easton Amber
Ian Novick Pfizer Trainee #3
Steven Rosenblum Editor
Anna Behlmer Sound Re-Recording Mixer
Bobby Stewart Stunts
Deborah L. Scott Costume Design
Jackson Nunn Viagra Guy #2 (uncredited)
Randall Poster Music Supervisor
Morgan Wolk Lilly Spokesmodel (uncredited)
John A. Larsen Supervising Sound Editor
John W. Iwanonkiw Viagra Guy (uncredited)
Adam Wood Stunts
Scott Stuber Producer
Pieter Jan Brugge Producer, Unit Production Manager
David James Additional Still Photographer
Bingo O'Malley Sam
Gary Kosko Art Direction
Tess Soltau Pfizer Trainee #4
Alan Munro Visual Effects Supervisor
Harry O'Toole Man with Walker
Constance Brenneman Pfizer Trainee #5
Vanessa Aspillaga Viagra Nurse #3
Daren Dochterman VFX Artist
Karen Lovell Hairstylist
Ray Bivins Special Effects Coordinator
Yesi Ramirez Casting Associate
Meg Everist Set Decoration
Donna Belajac Casting
Loretta Higgins PET Scan Doctor
Rebecca Robertson Script Supervisor
Jerry Popolis Hairstylist