George López Grouchy Smurf (voice)
Frank Welker Azrael (voice)
Hank Azaria Gargamel
Neil Patrick Harris Patrick Winslow
Alan Cumming Gutsy Smurf (voice)
Paul Reubens Jokey Smurf (voice)
Sofía Vergara Odile Anjelou
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
Kenan Thompson Greedy Smurf (voice)
Jayma Mays Grace Winslow
Fred Armisen Brainy Smurf (voice)
John Oliver Vanity Smurf (voice)
B.J. Novak Baker Smurf (voice)
Joan Rivers Party Guest
John Cenatiempo Stunts
John Kassir Crazy Smurf (Voice)
Sean Kenin Guy in Plaid Shirt
Skai Jackson Kicking Girl
Tom Kane Narrator Smurf (voice)
Tim Gunn Henri
J. David Stem Screenplay, Story
Jonathan Winters Papa Smurf (voice)
Madison McKinley Model
Joel McCrary Farmer Smurf (voice)
David N. Weiss Story, Screenplay
Gary Basaraba Hefty Smurf (voice)
Jay Scherick Screenplay
Raja Gosnell Director
John Speredakos Parent with Girls
David Rubin Casting
Sean Ringgold Inmate Bubba
David Ronn Screenplay
Peyo Characters, Comic Book
Richard Hicks Casting
Jerad Marantz Makeup Designer
Jeff Foxworthy Handy Smurf (voice)
Heitor Pereira Original Music Composer
Mo Henry Negative Cutter
Heidi Armbruster Toy Store Parent
Aja Frary Stunts
Sabrina Plisco Editor
Mario D'Leon Bubba's Inmate Friend
Wolfgang Puck Chef Smurf (voice)
Bradley Gosnell Toy Salesperson
Tudor Jones First Assistant Director
Jill Brown Stunts
Tom Colicchio Party Guest
Jojo Gonzalez FAO Custodian
Chris Cenatiempo Stunts
Michael Musto Party Guest
Ronni Brown Foley Artist
Sarah Monat Foley Artist
Victor Pagan Bum
Bill Boes Production Design
Shawnna Thibodeau Stunts
David M. Dunlap Second Unit Director
G.A. Aguilar Stunt Coordinator, Second Unit Director
Todd Tucker Makeup Designer
Phil Meheux Director of Photography
Jordan Kerner Producer
Chris Shriver Art Direction
Andrew Sellon Waiter
Mark Doherty Bluetooth Businessman
Aaron Williams VFX Artist
Justin Ritson Additional Second Assistant Director
Peter Thorell Second Assistant Director
Frederic Roth First Assistant Director
Benita Allen First Assistant Director
Julie Chang Newscaster
Jayne Armstrong Post Production Supervisor
Regina Graves Set Decoration