Sofía Vergara Odile Anjelou
Alan Cumming Gutsy Smurf (voice)
George López Grouchy Smurf (voice)
Hank Azaria Gargamel
Frank Welker Azrael (voice)
Fred Armisen Brainy Smurf (voice)
Kenan Thompson Greedy Smurf (voice)
Tim Gunn Henri
Neil Patrick Harris Patrick Winslow
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
B.J. Novak Baker Smurf (voice)
Jayma Mays Grace Winslow
Paul Reubens Jokey Smurf (voice)
John Cenatiempo Stunts
John Kassir Crazy Smurf (Voice)
Heidi Armbruster Toy Store Parent
Tom Kane Narrator Smurf (voice)
Madison McKinley Model
Gary Basaraba Hefty Smurf (voice)
Christian Wintter Art Direction
John Oliver Vanity Smurf (voice)
Skai Jackson Kicking Girl
Jeff Foxworthy Handy Smurf (voice)
Joel McCrary Farmer Smurf (voice)
Joan Rivers Party Guest
Raja Gosnell Director
J. David Stem Screenplay, Story
Sean Ringgold Inmate Bubba
Jay Scherick Screenplay
Peyo Characters, Comic Book
Yuhon Ng Animation
Tudor Jones First Assistant Director
Sarah Monat Foley Artist
Peter Thorell Second Assistant Director
Jonathan Winters Papa Smurf (voice)
Victor Pagan Bum
David Ronn Screenplay
David N. Weiss Screenplay, Story
Richard Hicks Casting
Chris Cenatiempo Stunts
Jill Brown Stunts
Mo Henry Negative Cutter
Wolfgang Puck Chef Smurf (voice)
Jerad Marantz Makeup Designer
Heitor Pereira Original Music Composer
Conor Kelly Second Second Assistant Director
Bill Boes Production Design
Jordan Kerner Producer
Aja Frary Stunts
David M. Dunlap Second Unit Director
John Speredakos Parent with Girls
Regina Graves Set Decoration
G.A. Aguilar Second Unit Director, Stunt Coordinator
Mark Doherty Bluetooth Businessman
Tyree Michael Simpson Cop
David Rubin Casting
Shawnna Thibodeau Stunts
Sean Kenin Guy in Plaid Shirt
Julie Chang Newscaster
Phil Meheux Director of Photography
Ronni Brown Foley Artist
Chris Shriver Art Direction
Todd Tucker Makeup Designer
Mario D'Leon Bubba's Inmate Friend
Mahadeo Shivraj Cabbie
Justin Ritson Additional Second Assistant Director
Richard Baratta Unit Production Manager
Bradley Gosnell Toy Salesperson
Jimmy Almeida Animation
Ezra Swerdlow Executive Producer
Benita Allen First Assistant Director