Alan Cumming Gutsy Smurf (voice)
Frank Welker Azrael (voice)
Sofía Vergara Odile Anjelou
Neil Patrick Harris Patrick Winslow
Jayma Mays Grace Winslow
George López Grouchy Smurf (voice)
Tom Kane Narrator Smurf (voice)
Hank Azaria Gargamel
Fred Armisen Brainy Smurf (voice)
Jeff Foxworthy Handy Smurf (voice)
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
John Cenatiempo Stunts
Kenan Thompson Greedy Smurf (voice)
Paul Reubens Jokey Smurf (voice)
John Oliver Vanity Smurf (voice)
B.J. Novak Baker Smurf (voice)
John Kassir Crazy Smurf (Voice)
J. David Stem Screenplay, Story
Raja Gosnell Director
Gary Basaraba Hefty Smurf (voice)
Tim Gunn Henri
David Ronn Screenplay
Skai Jackson Kicking Girl
Sean Kenin Guy in Plaid Shirt
David N. Weiss Screenplay, Story
Joel McCrary Farmer Smurf (voice)
Mo Henry Negative Cutter
Joan Rivers Party Guest
Madison McKinley Model
Chris Shriver Art Direction
G.A. Aguilar Second Unit Director, Stunt Coordinator
Heidi Armbruster Toy Store Parent
Richard Hicks Casting
Yuhon Ng Animation
Ronni Brown Foley Artist
David Rubin Casting
Jay Scherick Screenplay
Christian Wintter Art Direction
John Speredakos Parent with Girls
Shawnna Thibodeau Stunts
Todd Tucker Makeup Designer
Sean Ringgold Inmate Bubba
Jojo Gonzalez FAO Custodian
Phil Meheux Director of Photography
Sarah Monat Foley Artist
David M. Dunlap Second Unit Director
Chris Cenatiempo Stunts
Tudor Jones First Assistant Director
Regina Graves Set Decoration
Aja Frary Stunts
Bill Boes Production Design
Heitor Pereira Original Music Composer
Jill Brown Stunts
Mahadeo Shivraj Cabbie
Peyo Characters, Comic Book
Peter Thorell Second Assistant Director
Mark Doherty Bluetooth Businessman
Ezra Swerdlow Executive Producer
Richard Baratta Unit Production Manager
Jordan Kerner Producer
Rita Ryack Costume Design
Jonathan Winters Papa Smurf (voice)
Tyree Michael Simpson Cop
Benita Allen First Assistant Director
Victor Pagan Bum
Mike Dharney Animation
Jerad Marantz Makeup Designer
Scott Dillin Cop
Justin Ritson Additional Second Assistant Director
Sabrina Plisco Editor
Andy Hass Animation