Sofía Vergara Odile Anjelou
Alan Cumming Gutsy Smurf (voice)
Frank Welker Azrael (voice)
Kenan Thompson Greedy Smurf (voice)
Hank Azaria Gargamel
Neil Patrick Harris Patrick Winslow
Tim Gunn Henri
Jayma Mays Grace Winslow
B.J. Novak Baker Smurf (voice)
John Kassir Crazy Smurf (Voice)
George López Grouchy Smurf (voice)
Skai Jackson Kicking Girl
Anton Yelchin Clumsy Smurf (voice)
John Cenatiempo Stunts
Joan Rivers Party Guest
Heidi Armbruster Toy Store Parent
Katy Perry Smurfette (voice)
Fred Armisen Brainy Smurf (voice)
Jojo Gonzalez FAO Custodian
Christian Wintter Art Direction
John Oliver Vanity Smurf (voice)
Gary Basaraba Hefty Smurf (voice)
Paul Reubens Jokey Smurf (voice)
Jeff Foxworthy Handy Smurf (voice)
Madison McKinley Model
Sean Kenin Guy in Plaid Shirt
Jonathan Winters Papa Smurf (voice)
Victor Pagan Bum
Raja Gosnell Director
Sean Ringgold Inmate Bubba
Joel McCrary Farmer Smurf (voice)
Aja Frary Stunts
Tom Kane Narrator Smurf (voice)
Jayne Armstrong Post Production Supervisor
Todd Tucker Makeup Designer
Heitor Pereira Original Music Composer
Conor Kelly Second Second Assistant Director
David N. Weiss Screenplay, Story
J. David Stem Screenplay, Story
David Rubin Casting
Chris Cenatiempo Stunts
Sarah Monat Foley Artist
Julie Chang Newscaster
Bill Boes Production Design
David M. Dunlap Second Unit Director
Peyo Characters, Comic Book
John Speredakos Parent with Girls
Mark Doherty Bluetooth Businessman
Mo Henry Negative Cutter
Peter Thorell Second Assistant Director
Wolfgang Puck Chef Smurf (voice)
Mario D'Leon Bubba's Inmate Friend
Jill Brown Stunts
Bradley Gosnell Toy Salesperson
G.A. Aguilar Stunt Coordinator, Second Unit Director
Tyree Michael Simpson Cop
Scott Dillin Cop
Chris Shriver Art Direction
David Ronn Screenplay
Jerad Marantz Makeup Designer
Tom Colicchio Party Guest
Shawnna Thibodeau Stunts
Ezra Swerdlow Executive Producer
Andrew Sellon Waiter
Jay Scherick Screenplay
Phil Meheux Director of Photography
Benita Allen First Assistant Director
Aaron Williams VFX Artist
Finnerty Steeves Toy Store Parent
Michael Musto Party Guest
Yuhon Ng Animation
Ronni Brown Foley Artist