Sofía Vergara Odile Anjelou
George López Grouchy Smurf (voice)
Frank Welker Azrael (voice)
Alan Cumming Gutsy Smurf (voice)
Hank Azaria Gargamel
Neil Patrick Harris Patrick Winslow
Tim Gunn Henri
Fred Armisen Brainy Smurf (voice)
B. J. Novak Baker Smurf (voice)
Anton Yelchin Clumsy Smurf (voice)
Katy Perry Smurfette (voice)
Jayma Mays Grace Winslow
Kenan Thompson Greedy Smurf (voice)
John Cenatiempo Stunts
Skai Jackson Kicking Girl
Paul Reubens Jokey Smurf (voice)
Tom Kane Narrator Smurf (voice)
Heidi Armbruster Toy Store Parent
John Kassir Crazy Smurf (Voice)
Madison McKinley Model
Mark Doherty Bluetooth Businessman
Christian Wintter Art Direction
David N. Weiss Screenplay, Story
Joan Rivers Party Guest
Gary Basaraba Hefty Smurf (voice)
Raja Gosnell Director
Joel McCrary Farmer Smurf (voice)
John Oliver Vanity Smurf (voice)
J. David Stem Screenplay, Story
Jeff Foxworthy Handy Smurf (voice)
Jill Brown Stunts
Peyo Characters, Comic Book
David Ronn Screenplay
David M. Dunlap Second Unit Director
Jonathan Winters Papa Smurf (voice)
Victor Pagan Bum
G.A. Aguilar Second Unit Director, Stunt Coordinator
Heitor Pereira Original Music Composer
Jay Scherick Screenplay
Sean Ringgold Inmate Bubba
Aja Frary Stunts
Chris Cenatiempo Stunts
Ronni Brown Foley Artist
Tyree Michael Simpson Cop
Wolfgang Puck Chef Smurf (voice)
Conor Kelly Second Second Assistant Director
Julie Chang Newscaster
Jerad Marantz Makeup Designer
David Rubin Casting
Mo Henry Negative Cutter
Shawnna Thibodeau Stunts
Jordan Kerner Producer
Frederic Roth First Assistant Director
Mario D'Leon Bubba's Inmate Friend
Bradley Gosnell Toy Salesperson
John Speredakos Parent with Girls
Todd Tucker Makeup Designer
Justin Ritson Additional Second Assistant Director
Peter Thorell Second Assistant Director
Jimmy Almeida Animation
Regina Graves Set Decoration
Phil Meheux Director of Photography
Sarah Monat Foley Artist
Sean Kenin Guy in Plaid Shirt
Rita Ryack Costume Design
Tudor Jones First Assistant Director
Finnerty Steeves Toy Store Parent
Elise de Blois Set Decoration
Tom Colicchio Party Guest
Jojo Gonzalez FAO Custodian
Richard Baratta Unit Production Manager
Chris Shriver Art Direction