Mckenna Grace Young Daphne (voice)
Mark Wahlberg Blue Falcon (voice)
Amanda Seyfried Daphne Blake (voice)
Jason Isaacs Dick Dastardly (voice)
Zac Efron Fred Jones (voice)
Christina Hendricks Officer Jaffe (voice)
Ariana Greenblatt Young Velma (voice)
Iain Armitage Young Shaggy (voice)
Ken Jeong Dynomutt (voice)
John DiMaggio Restaurant Owner (voice)
Will Forte Shaggy Rogers (voice)
Chris Columbus Executive Producer
Frank Welker Scooby-Doo / Pterodactyl (voice)
Henry Winkler Keith (voice)
Fred Tatasciore Cerberus (voice)
Tracy Morgan Captain Caveman (voice)
Justina Machado Jamie Rivera (voice)
Gina Rodriguez Velma Dinkley (voice)
Billy West Muttley (voice)
Kiersey Clemons Dee Dee Skyes (voice)
Dan Povenmire Executive Producer
Charlie Puth Songs
Pierce Gagnon Young Fred (voice)
Kevin Heffernan Bike Cop Gary (voice)
Simon Cowell Simon Cowell (voice)
Don Messick Muttley (archive sound) (voice)
Maya Erskine Judy Takamoto (voice)
Tom Holkenborg Original Music Composer
Tony Cervone Director, Ghost / Mr. Rigby / Alice (voice)
Eyal Podell Story
Charles Roven Executive Producer
Matt Lieberman Screenplay, Story
Richard Suckle Executive Producer
Ira Glass Ira Glass (voice)
Jack Harlow Songs
Joe Ruby Characters
Adam Sztykiel Officer Casey (voice), Screenplay, Executive Producer
Gabe Hilfer Music Supervisor
Ruth Lambert Casting
Ricardo F. Delgado Storyboard Artist
Noëlle Raffaele Story Artist
Allison Abbate Producer
Jack C. Donaldson Screenplay
Ken Spears Characters
Vanara Taing Baby Rotten (voice), Editor
Ryan Folsey Beach Guy (voice), Editor
Ava Max Songs
Tom Ruegger Art Designer, Visual Effects Designer
Rico Nasty Songs
Didier Ah-Koon Storyboard Artist
Jesse Ehrman Executive Producer
Jonathon E. Stewart Story
Harry Perry Harry Perry (voice)
Andy Horwitz Executive Producer
Chiranjiv Makwana Screenplay
Maven Morgan Kari (voice)
Derek Elliott Screenplay
Tony Cosanella Co-Producer
Henry Kaufman Chad / Chet (voice)
Michael Kurinsky Samuel Colton (voice), Production Design
Pink Sweat$ Songs
Pam Coats Mrs. Rogers (voice), Producer
Lex Cassar Visual Development
Rafael Zentil Head of Story
Eric Cowell Ben (voice)
Joe Haidar Storyboard Artist
Emil Mitev Art Direction
Alex Kauffman Officer North (voice)
Bill Haller Head of Animation
Danelle Davenport Storyboard Artist
John McDaniel Hal Murphy (voice)
Sarah Lancia Dispatcher Stevens (voice)