Mckenna Grace Young Daphne (voice)
Mark Wahlberg Blue Falcon (voice)
Amanda Seyfried Daphne Blake (voice)
Frank Welker Scooby-Doo / Pterodactyl (voice)
Christina Hendricks Officer Jaffe (voice)
Jason Isaacs Dick Dastardly (voice)
Will Forte Shaggy Rogers (voice)
Zac Efron Fred Jones (voice)
John DiMaggio Restaurant Owner (voice)
Henry Winkler Keith (voice)
Ken Jeong Dynomutt (voice)
Iain Armitage Young Shaggy (voice)
Billy West Muttley (voice)
Ariana Greenblatt Young Velma (voice)
Fred Tatasciore Cerberus (voice)
Tracy Morgan Captain Caveman (voice)
Justina Machado Jamie Rivera (voice)
Gina Rodriguez Velma Dinkley (voice)
Ricardo F. Delgado Storyboard Artist
Kiersey Clemons Dee Dee Skyes (voice)
Chris Columbus Executive Producer
Simon Cowell Simon Cowell (voice)
Eyal Podell Story
Maya Erskine Judy Takamoto (voice)
Don Messick Muttley (archive sound) (voice)
Pierce Gagnon Young Fred (voice)
Tony Cosanella Co-Producer
Ira Glass Ira Glass (voice)
Dan Povenmire Executive Producer
Kevin Heffernan Bike Cop Gary (voice)
Charles Roven Executive Producer
Gabe Hilfer Music Supervisor
Tom Ruegger Art Designer, Visual Effects Designer
Ruth Lambert Casting
Ken Spears Characters
Tom Holkenborg Original Music Composer
Tony Cervone Director, Ghost / Mr. Rigby / Alice (voice)
Charlie Puth Songs
Adam Sztykiel Officer Casey (voice), Screenplay, Executive Producer
Matt Lieberman Screenplay, Story
Joe Ruby Characters
Ava Max Songs
Henry Kaufman Chad / Chet (voice)
Danelle Davenport Storyboard Artist
Joe Haidar Storyboard Artist
Jesse Ehrman Executive Producer
Allison Abbate Producer
Richard Suckle Executive Producer
Jack Harlow Songs
Noëlle Raffaele Story Artist
Vanara Taing Baby Rotten (voice), Editor
Ryan Folsey Beach Guy (voice), Editor
Michael Kurinsky Samuel Colton (voice), Production Design
Chiranjiv Makwana Screenplay
Emil Mitev Art Direction
Timothy Jason Smith Associate Producer
Lex Cassar Visual Development
Jonathon E. Stewart Story
Pam Coats Mrs. Rogers (voice), Producer
Didier Ah-Koon Storyboard Artist
Derek Elliott Screenplay
Rico Nasty Songs
Jack C. Donaldson Screenplay
Harry Perry Harry Perry (voice)
Maven Morgan Kari (voice)
Bill Haller Head of Animation
Pink Sweat$ Songs
Rafael Zentil Head of Story
Andy Horwitz Executive Producer
Kennedy Peil Indira Knight (voice)
Stephen W. Childers Head of Layout
Mike Fortner CG Supervisor