Mckenna Grace Young Daphne (voice)
Amanda Seyfried Daphne Blake (voice)
Mark Wahlberg Blue Falcon (voice)
Jason Isaacs Dick Dastardly (voice)
Christina Hendricks Officer Jaffe (voice)
Zac Efron Fred Jones (voice)
Ariana Greenblatt Young Velma (voice)
Iain Armitage Young Shaggy (voice)
Ken Jeong Dynomutt (voice)
Frank Welker Scooby-Doo / Pterodactyl (voice)
Chris Columbus Executive Producer
Will Forte Shaggy Rogers (voice)
Tracy Morgan Captain Caveman (voice)
Henry Winkler Keith (voice)
Fred Tatasciore Cerberus (voice)
Justina Machado Jamie Rivera (voice)
John DiMaggio Restaurant Owner (voice)
Billy West Muttley (voice)
Kiersey Clemons Dee Dee Skyes (voice)
Dan Povenmire Executive Producer
Gina Rodriguez Velma Dinkley (voice)
Charlie Puth Songs
Pierce Gagnon Young Fred (voice)
Kevin Heffernan Bike Cop Gary (voice)
Simon Cowell Simon Cowell (voice)
Don Messick Muttley (archive sound) (voice)
Maya Erskine Judy Takamoto (voice)
Eyal Podell Story
Tom Holkenborg Original Music Composer
Charles Roven Executive Producer
Matt Lieberman Screenplay, Story
Ira Glass Ira Glass (voice)
Gabe Hilfer Music Supervisor
Jack Harlow Songs
Joe Ruby Characters
Tony Cervone Director, Ghost / Mr. Rigby / Alice (voice)
Ruth Lambert Casting
Adam Sztykiel Officer Casey (voice), Screenplay, Executive Producer
Ricardo F. Delgado Storyboard Artist
Noëlle Raffaele Story Artist
Allison Abbate Producer
Jack C. Donaldson Screenplay
Ken Spears Characters
Ryan Folsey Beach Guy (voice), Editor
Chiranjiv Makwana Screenplay
Ava Max Songs
Tom Ruegger Art Designer, Visual Effects Designer
Richard Suckle Executive Producer
Jesse Ehrman Executive Producer
Rico Nasty Songs
Vanara Taing Baby Rotten (voice), Editor
Didier Ah-Koon Storyboard Artist
Jonathon E. Stewart Story
Harry Perry Harry Perry (voice)
Maven Morgan Kari (voice)
Derek Elliott Screenplay
Tony Cosanella Co-Producer
Henry Kaufman Chad / Chet (voice)
Michael Kurinsky Samuel Colton (voice), Production Design
Pink Sweat$ Songs
Andy Horwitz Executive Producer
Pam Coats Mrs. Rogers (voice), Producer
Lex Cassar Visual Development
Rafael Zentil Head of Story
Emil Mitev Art Direction
Eric Cowell Ben (voice)
Joe Haidar Storyboard Artist
Alex Kauffman Officer North (voice)
Bill Haller Head of Animation
Danelle Davenport Storyboard Artist
John McDaniel Hal Murphy (voice)
Sarah Lancia Dispatcher Stevens (voice)