Mckenna Grace Young Daphne (voice)
Mark Wahlberg Blue Falcon (voice)
Amanda Seyfried Daphne Blake (voice)
Frank Welker Scooby-Doo / Pterodactyl (voice)
Jason Isaacs Dick Dastardly (voice)
Christina Hendricks Officer Jaffe (voice)
John DiMaggio Restaurant Owner (voice)
Will Forte Shaggy Rogers (voice)
Zac Efron Fred Jones (voice)
Henry Winkler Keith (voice)
Ken Jeong Dynomutt (voice)
Iain Armitage Young Shaggy (voice)
Billy West Muttley (voice)
Fred Tatasciore Cerberus (voice)
Ariana Greenblatt Young Velma (voice)
Justina Machado Jamie Rivera (voice)
Tracy Morgan Captain Caveman (voice)
Kiersey Clemons Dee Dee Skyes (voice)
Chris Columbus Executive Producer
Gina Rodriguez Velma Dinkley (voice)
Ricardo F. Delgado Storyboard Artist
Tony Cosanella Co-Producer
Simon Cowell Simon Cowell (voice)
Maya Erskine Judy Takamoto (voice)
Eyal Podell Story
Pierce Gagnon Young Fred (voice)
Don Messick Muttley (archive sound) (voice)
Kevin Heffernan Bike Cop Gary (voice)
Gabe Hilfer Music Supervisor
Charles Roven Executive Producer
Dan Povenmire Executive Producer
Tom Ruegger Art Designer, Visual Effects Designer
Ruth Lambert Casting
Tony Cervone Director, Ghost / Mr. Rigby / Alice (voice)
Tom Holkenborg Original Music Composer
Charlie Puth Songs
Ava Max Songs
Joe Ruby Characters
Matt Lieberman Screenplay, Story
Ira Glass Ira Glass (voice)
Adam Sztykiel Officer Casey (voice), Screenplay, Executive Producer
Ken Spears Characters
Joe Haidar Storyboard Artist
Henry Kaufman Chad / Chet (voice)
Jesse Ehrman Executive Producer
Allison Abbate Producer
Richard Suckle Executive Producer
Vanara Taing Baby Rotten (voice), Editor
Jack Harlow Songs
Noëlle Raffaele Story Artist
Danelle Davenport Storyboard Artist
Ryan Folsey Beach Guy (voice), Editor
Emil Mitev Art Direction
Chiranjiv Makwana Screenplay
Timothy Jason Smith Associate Producer
Michael Kurinsky Samuel Colton (voice), Production Design
Didier Ah-Koon Storyboard Artist
Pam Coats Mrs. Rogers (voice), Producer
Lex Cassar Visual Development
Jonathon E. Stewart Story
Rico Nasty Songs
Bill Haller Head of Animation
Harry Perry Harry Perry (voice)
Pink Sweat$ Songs
Maven Morgan Kari (voice)
Derek Elliott Screenplay
Rafael Zentil Head of Story
Jack C. Donaldson Screenplay
Andy Horwitz Executive Producer
Kennedy Peil Indira Knight (voice)
Mike Fortner CG Supervisor
Eric Cowell Ben (voice)