Mila Kunis Amy
Kathryn Hahn Carla
Kristen Bell Kiki
Christina Applegate Gwendolyn
Jay Hernandez Jessie Harkness
Wendell Pierce Principal Burr
Jada Pinkett Smith Stacy
Jon Lucas Writer, Director
Oona Laurence Jane
Colin Egglesfield Astronaut
Clark Duke Dale Kipler
Wanda Sykes Dr. Karl
Megan Ferguson Tessa
Lilly Singh Cathy
Emjay Anthony Dylan
David Walton Mike
Taryn Terrell Stunt Double
Leah McKendrick Sharon
Scott Moore Director, Writer
Annie Mumolo Vicky
Mark Kamine Executive Producer
Alvin Chon Stunts
Martha Stewart Martha Stewart
Christina DeRosa Heather
Oren Aviv Executive Producer
Wang Zhong Lei Executive Producer
Billy Slaughter Veterinarian
Ann Mahoney Mousey Mom
Emma E. Hickox Editor
Christopher Lennertz Original Music Composer
Jaylen Moore Steve
Jim Denault Director of Photography
Chelsea Bruland Stunt Driver
Eugenia Kuzmina Alina
Yan Feldman Bartender
Lena Clark Departing Mom
Crystal Hooks Stunt Double
Lara Grice Tired Mom
Cathy Sandrich Gelfond Casting
Donna DuPlantier Vera
Lyle Brocato Kent
Lindsey Garrett Intense Mom
Adria Tennor Conservative Mom
Michele Ziegler Diane, First Assistant Director
Jackie Tuttle Mom Janet
Carrie Lazar Strange Mother
Chris J. Fanguy Stunt Driver
Suzanne Todd Producer
Paul Hughen Second Unit Director of Photography
Meghan Wolfe Donut Hole Kid
Bill Block Producer
Ashley Nicole Hudson Stunts
Amanda Mackey Casting
Dara Taylor Music Producer
Jay Jablonski Man in Suit
Kelly Phelan Stunt Double
James Thomas Editor
Nancy Priddy Christina Applegate's Mom
Regis Harrington Stunt Driver
Scott Plauche Art Direction
Samantha Beaulieu Tiger Mom
Amy Brassette Drunk Mom
Francesca Buccellato Key Makeup Artist
Kelly Lind Audrey
Mitch Landrieu Thanks
Julia Michels Music Supervisor
Robert Simonds Executive Producer
David Simpson Monotone Hipster
J.J. Watt Coach Craig
Tyler Galpin Stunt Driver
Shauna Rappold Business Mom
Donna Spahn Hairstylist