Tom Cruise Frank T.J. Mackey
Alfred Molina Solomon Solomon
Julianne Moore Linda Partridge
William H. Macy Quiz Kid Donnie Smith
Luis Guzmán Luis
Philip Seymour Hoffman Phil Parma
Patton Oswalt Delmer Darion
John C. Reilly Officer Jim Kurring
Mary Lynn Rajskub Janet (Frank's Assistant) (voice)
Thomas Jane Young Jimmy Gator
Debbie Evans Stunts
Neil Flynn Stanley Berry
Paul Thomas Anderson Director, Writer, Man Confiscating Sign (uncredited), Producer
James Ashwill Foley Mixer
Phil Culotta Stunts
Chris O'Hara Sydney Barringer
Thomas J. O'Connell ADR Mixer
Chris L. Spellman Set Decoration
William Mapother WDKK Show Director's Assistant
Clark Gregg WDKK Floor Director
Christopher Allen Nelson Special Effects Makeup Artist
Richard L. Hill Special Effects
Jim Meskimen Forensic Scientist
Jim Beaver Smiling Peanut Patron #1
Rick Seaman Stunts
Bob Yerkes Stunts
Orlando Jones Worm
Paul F. Tompkins Chad (Seduce & Destroy) (voice)
John T. Cucci Foley Artist
Melora Walters Claudia Wilson Gator
Philip Baker Hall Jimmy Gator
Michael De Luca Executive Producer
Michael Bowen Rick Spector
Matt Gerald Officer #2
Jack Carpenter Stunts
Jason Robards Earl Partridge
Charlie Scott Jr. Craft Service, Pedestrian #2
Felicity Huffman Cynthia
Miriam Margolyes Faye Barringer (uncredited)
J. Armin Garza II Camera Car
Hugh Aodh O'Brien Stunts
Meagen Fay Dr. Diane
Melinda Dillon Rose Gator
Timothy S. Wiles Property Master
April Grace Gwenovier
David M. Roberts Boom Operator
Ken Tarallo Special Effects
Kelvin R. Trahan Key Hair Stylist
Don McManus Dr. Landon
Dan O'Connell Foley Artist
Robert J. Carlyle Construction Coordinator
Daniel Lupi Co-Producer, Unit Production Manager
Spencer Kayden Seminar Patron (uncredited)
Allan Graf Stunts, Firefighter
Cleo King Marcie
Jennifer Clark Assistant Accountant
Michael Lee Phillips Jr. Set Production Assistant, Mackey Disciple in Middle
Robert J. Litt Sound Re-Recording Mixer
Richard F. Anderson Set Dresser
Paul C. Babin Camera Operator
Michael Herbick Sound Re-Recording Mixer
Barbara Harris ADR Voice Casting
P. Scott Bailey Props
Joe Letteri Visual Effects Supervisor
Kelly A. Snyder Production Accountant
John Pritchett Sound Mixer, Police Captain
Michael Murphy Alan Kligman, Esq.
Tina Roesler Kerwin Key Makeup Artist
Hans Bjerno Aerial Camera
Pat Healy Sir Edmund William Godfrey / Young Pharmacy Kid
Robert Downey Sr. WDKK Show Director
Michael Shamus Wiles Captain Muffy