Tom Cruise Frank T.J. Mackey
Julianne Moore Linda Partridge
Hugh Aodh O'Brien Stunts
Cleo King Marcie
William H. Macy Quiz Kid Donnie Smith
Luis Guzmán Luis
Miriam Margolyes Faye Barringer (uncredited)
Paul Thomas Anderson Man Confiscating Sign (uncredited), Director, Producer, Writer
Thomas Jane Young Jimmy Gator
Philip Seymour Hoffman Phil Parma
John C. Reilly Officer Jim Kurring
Orlando Jones Worm
Mary Lynn Rajskub Janet (Frank's Assistant) (voice)
Alfred Molina Solomon Solomon
Melora Walters Claudia Wilson Gator
William Mapother WDKK Show Director's Assistant
Michael Bowen Rick Spector
Neil Flynn Stanley Berry
Jim Beaver Smiling Peanut Patron #1
Jason Robards Earl Partridge
Don McManus Dr. Landon
Felicity Huffman Cynthia
Clark Gregg WDKK Floor Director
Chris O'Hara Sydney Barringer
Melinda Dillon Rose Gator
Michael Shamus Wiles Captain Muffy
Thomas J. O'Connell ADR Mixer
Paul F. Tompkins Chad (Seduce & Destroy) (voice)
Dennis Sands Scoring Mixer
Jennifer Clark Assistant Accountant
Michael Murphy Alan Kligman, Esq.
Miguel Pérez Avi Solomon
Patton Oswalt Delmer Darion
Terry Jackson Stunts
Allan Graf Firefighter, Stunts
Matt Gerald Officer #2
Pat Healy Sir Edmund William Godfrey / Young Pharmacy Kid
Paul Prokop Production Controller
Greg Bronson Waiter (uncredited)
Barbara Harris ADR Voice Casting
Philip Baker Hall Jimmy Gator
Henry Gibson Thurston Howell
Meagen Fay Dr. Diane
Dylan Tichenor Editor, Associate Producer
Ezra Buzzington Smiling Peanut Patron #2
Ricky Jay Burt Ramsey / Narrator
April Grace Gwenovier
Lillian Adams Donnie's Old Neighbor
John S. Davies Cameraman
Christopher Allen Nelson Special Effects Makeup Artist
Michael De Luca Executive Producer
Joseph Grossberg Visual Effects Producer
Richard Burden Stunts
Robert Elswit Director of Photography
Hans Bjerno Aerial Camera
Rod McLachlan Daniel Hill
Daniel Lupi Unit Production Manager, Co-Producer
Robert Downey Sr. WDKK Show Director
Michael Adams Stunts
Debbie Evans Stunts
Brad Hunt Craig Hansen
Spencer Kayden Seminar Patron (uncredited)
Jon Brion Original Music Composer
Ousaun Elam Stunts
Aimee Mann Hot Date Infomercial (uncredited), Songs
Tony Vandenecker Special Effects
Jim Meskimen Forensic Scientist
Clement Blake Arthur Barringer
Eileen Malyszko Lee Production Coordinator
Phil Culotta Stunts
Lorin Flemming Chef
Kevin Breznahan Geoff, Seminar Guy