Tom Cruise Frank T.J. Mackey
William H. Macy Quiz Kid Donnie Smith
Cleo King Marcie
Julianne Moore Linda Partridge
Luis Guzmán Luis
Alfred Molina Solomon Solomon
Paul Thomas Anderson Director, Producer, Writer, Man Confiscating Sign (uncredited)
Miriam Margolyes Faye Barringer (uncredited)
Thomas Jane Young Jimmy Gator
Paul F. Tompkins Chad (Seduce & Destroy) (voice)
Orlando Jones Worm
Philip Seymour Hoffman Phil Parma
Mary Lynn Rajskub Janet (Frank's Assistant) (voice)
William Mapother WDKK Show Director's Assistant
Michael Bowen Rick Spector
Neil Flynn Stanley Berry
Clark Gregg WDKK Floor Director
John C. Reilly Officer Jim Kurring
Jason Robards Earl Partridge
Don McManus Dr. Landon
Jim Beaver Smiling Peanut Patron #1
Patton Oswalt Delmer Darion
Felicity Huffman Cynthia
Scott Alan Smith E.R. Doctor
Dennis Sands Scoring Mixer
Melinda Dillon Rose Gator
Michael Shamus Wiles Captain Muffy
Melora Walters Claudia Wilson Gator
Jennifer Clark Assistant Accountant
Michael Murphy Alan Kligman, Esq.
Miguel Pérez Avi Solomon
Allan Graf Stunts, Firefighter
Hans Bjerno Aerial Camera
Matt Gerald Officer #2
Chris O'Hara Sydney Barringer
Pat Healy Sir Edmund William Godfrey / Young Pharmacy Kid
Paul Prokop Production Controller
Greg Bronson Waiter (uncredited)
Philip Baker Hall Jimmy Gator
Henry Gibson Thurston Howell
Meagen Fay Dr. Diane
Terry Jackson Stunts
Ricky Jay Burt Ramsey / Narrator
Barbara Harris ADR Voice Casting
Jim Meskimen Forensic Scientist
Lillian Adams Donnie's Old Neighbor
Tom Tangen Drunken Dart Player (uncredited)
April Grace Gwenovier
John S. Davies Cameraman
Dale Gibson Paramedic #3
Thomas J. O'Connell ADR Mixer
Joseph Grossberg Visual Effects Producer
Christopher Allen Nelson Special Effects Makeup Artist
Rod McLachlan Daniel Hill
Daniel Lupi Co-Producer, Unit Production Manager
Joe Letteri Visual Effects Supervisor
Robert Downey Sr. WDKK Show Director
Michael Adams Stunts
Brad Hunt Craig Hansen
Spencer Kayden Seminar Patron (uncredited)
Cassandra Kulukundis Casting
Ousaun Elam Stunts
Aimee Mann Songs, Hot Date Infomercial (uncredited)
Tony Vandenecker Special Effects
Clement Blake Arthur Barringer
Eileen Malyszko Lee Production Coordinator
Phil Culotta Stunts
Richard King Sound Designer, Supervising Sound Editor
Lorin Flemming Chef
Kevin Breznahan Geoff, Seminar Guy
Michael De Luca Executive Producer
Cory Buck Young Boy