Anne Hathaway Liz Curran
Jessica Alba Morley Clarkson
Emma Roberts Grace Smart
Julia Roberts Captain Kate Hazeltine
Shirley MacLaine Estelle Paddington
Kathleen Marshall Nikki
Jessica Biel Kara Monahan
Bradley Cooper Holden Wilson
Jamie Foxx Kelvin Moore
Eric Dane Sean Jackson
Jennifer Garner Julia Fitzpatrick
Ashton Kutcher Reed Bennett
Topher Grace Jason Morris
Patrick Dempsey Dr. Harrison Copeland
George López Alphonso Rodriguez
Katherine LaNasa Pamela Copeland
Kathy Bates Susan Milton
Taylor Lautner Willy Harrington
Queen Latifah Paula Thomas
Kristen Schaal Ms. Gilroy
Garry Marshall Director, Musician (uncredited)
Sandra Taylor Beach Girl Candy
Joe Mantegna Angry Driver (uncredited)
Calvin Jung Flower Mart Simon
Taylor Swift Felicia Miller
Larry Miller Oversized Baggage Agent
Sarah Lilly Lady With Dog
Emily Moss Wilson Kissing Girl (uncredited)
Wayne Allan Rice Producer
Héctor Elizondo Edgar Paddington
Howard Storm Louder Guy
Guilford Adams Vista Movie Theatre Owner (uncredited)
Megan Suri Rani
Paul Williams Romeo Midnight (voice)
Alexis Kendra Friend Dana
Emily Arlook Skater Girl (uncredited)
Bonnie Aarons Strange Lady
Aramis Knight (uncredited)
Derek Theler Masseur (uncredited)
Jennifer Leigh Warren Party Singer
Erin Matthews Flight Attendant
Deborah La Mia Denaver Makeup Department Head
Jonathan Morgan Heit Tough Franklin
Barbara Marshall Head Nurse
Larrs Jackson Chauffer Redmond
Kamilla Bjorlin Sherry Donaldson
Adrian Gorton Art Direction
Rance Howard Bistro Gardens Diner
Matthew Walker Greg Gilkins
Faline England Flower Shop Customer #1
Paul Vogt Shouting Sheldon
Matt Merchant Loud Guy
Angie Patterson Nanny (uncredited)
Christine Lakin Heather
Charles Minsky Director of Photography
Kelly Flynn Referee
Maryellen Aviano Extras Casting Coordinator
Cleo King TSA Supervisor Daisy Bell
Richard L. Anderson Sound Effects Editor
Cassie Rowell Coffee Barista
Robert Belushi Mailroom Ted
Eddie J. Fernandez Stunt Double
Mike Greenberg ESPN Radio Announcer #1 (voice)
Joey Sorge Amos
Carter Jenkins Alex Franklin
Lisa Roberts Gillan Young Nurse
Albert Brenner Production Design
Jennifer De Minco Cheerleader (uncredited)
Scott Marshall Mr. Schwabbe
Rick Batalla Michael
Marc Silverstein Writer
Scott Sener Cameraman #2