Will Smith Dr. Bennet Omalu
Alec Baldwin Dr. Julian Bailes
Richard T. Jones Andre Waters
Holt McCallany Angry Neurologist
Luke Wilson Roger Goodell
David Morse Mike Webster
Joe Fishel Louisville Head Football Coach
Albert Brooks Dr. Cyril Wecht
Paul Reiser Dr. Elliot Pellman
Ridley Scott Producer
Gugu Mbatha-Raw Prema Mutiso
Eddie Marsan Dr. Steven DeKosky
Stephen Moyer Dr. Ron Hamilton
Elizabeth Tulloch Keana Strzelczyk
Adewale Akinnuoye-Agbaje Dave Duerson
Dayna Pink Costume Design
Brittney Aleah Altar Server (uncredited)
Randy Kovitz Deputy Mayor
Hill Harper Christopher Jones
Peter Geraghty First Assistant Camera
Gary Grubbs FBI Agent
Rick Owens Foley
Stacy Caballero Assistant Costume Designer
Phillip Chorba Tech
Jay Kemp Gaffer
Doug Delaney Colorist
Dylan Goss Helicopter Camera
Matthew Willig Justin Strzelczyk
Joshua Elijah Reese Graveyard Tech
David Esparza Sound Designer
Jason Davis Defense Attorney
Michele C. Vallillo Visual Effects Producer
Arliss Howard Dr. Joseph Maroon
Christina Myal Assistant Art Director
Gary A. Hecker Foley
Robert G. McKay Mr. Scott (uncredited)
Mike O'Malley Daniel Sullivan
Marianne Skiba Makeup Artist
Michael Ford Visual Effects Supervisor
Nathan Hollabaugh Young Reporter
Dana Kay Hart Costume Supervisor
Elizabeth Cantillon Producer
L. Scott Caldwell Waters' Mother
Jared Scott Justin Strelczyk (uncredited)
Samara Lee Strzelczyk's Daughter
Melinda Sue Gordon Still Photographer
Mary Vernieu Casting
James Newton Howard Original Music Composer
Bruce Berman Executive Producer
Eme Ikwuakor Amobi Okoye (uncredited)
Dan Ziskie Paul Tagliabue
Michael Minkler Sound Re-Recording Mixer
Michelle Pazer Dialogue Editor
Christopher Boyer Crockett (uncredited)
Matthew Cavaliero Property Master
Andrew S. Eisen First Assistant Editor
Ben Waisbren Executive Producer
Kelley Davis Assistant
Joni Bovill Mrs. Scott
William Goldenberg Editor
John S. Moyer Camera Operator
Mike Clark TV Reporter (Interview)
Larry John Meyers Father D'Amico
Lindsay Graham Ahanonu Casting
David Crank Production Design
Chris Gallaher Makeup Effects
Salvatore Totino Director of Photography
Kathrine Gordon Hair Department Head
Jackson Nunn Church Member (uncredited)
Linda Weaver Casting Associate
Sara Lindsey Gracie
Judy Murdock Makeup Artist