Kaley Cuoco Eleanor (voice)
Anna Faris Jeanette (voice)
Jennifer Coolidge Ms. Price
Jason Lee Dave
Christina Applegate Brittany (voice)
Bella Thorne Ashley Grey
Justin Long Alvin (voice)
Uzo Aduba TSA Officer
Tony Hale Agent Suggs
Joshua Mikel Wyatt the Pizza Guy
Zeeko Zaki Paparazzi #2
Matthew Gray Gubler Simon (voice)
Laura Marano Hotel Babysitter
Jeremy Ray Taylor Kid
Kimberly Williams-Paisley Samantha
Jesse McCartney Theodore (voice)
John Waters First Class Passenger
Flula Borg Man Behind Mask
Hakim Callender Passing Record Executive
Retta Party Planner
Justin Miles Young Employee
Matthew O'Callaghan Animation Supervisor
Charmin Lee Judge
Eddie Steeples Barry
Greg Pitts Pool Attendant
Mark Mothersbaugh Original Music Composer
Adam Sztykiel Writer
Mark Jeffrey Miller Cab Driver
Edwin Rivera Visual Effects Supervisor
Mary Claire Hannan Costume Design
Randi Mayem Singer Writer
Arnon Milchan Executive Producer
Walt Becker Director
Janice Karman Characters, Producer, Theodore / The Chipettes (singing voice) (uncredited)
Peter Lyons Collister Director of Photography
Kevin Wayne Large Cowboy
Ross Bagdasarian Jr. Characters, Producer, Alvin (singing voice) (uncredited)
Keith Arthur Bolden Party Cop #2
Denitra Isler Ticket Agent
Manish Raval Music Supervisor
Joe Letteri Senior Visual Effects Supervisor
Ryan Kilgore Brass Band Member
John Lacy Owner
Doug Jackson Supervising Sound Editor
John H. Starke Executive Producer
Andrew Dorfman Music Editor
Candace B. Harris Airline Ticket Agent
Jackie Burch Casting
Paul D. Kelly Supervising Art Director
Jack Gill Stunt Coordinator
Sheila Jaffe Casting
Stefan Gordy DJ at Party
Caius Man Special Effects Coordinator
Galen Goodpaster Supervising Sound Editor
Ryan Folsey Editor
Steve Dubin Visual Effects Producer
Brice R. Parker Visual Effects Producer
Noelle Jean-Baptiste Set Decorating Coordinator
Tom Wolfe Music Supervisor
Josh Green Miles
Daniel Hargrave Stunts
Thomas E. Ackerman Second Unit Director
Frank Galline Set Decoration
Jennifer Teves Associate Producer
Jeff Carson Music Editor
Mike Senior Paparazzi #1
Leticia Jimenez Second Record Executive
Daryn Kahn Party Guy
Alana Da Fonseca Executive Music Producer
David DeSantos Maitre'd
Travis Pates Makeup Department Head
Karen Rosenfelt Executive Producer