Kaley Cuoco Eleanor (voice)
Anna Faris Jeanette (voice)
Justin Long Alvin (voice)
Jennifer Coolidge Ms. Price
Christina Applegate Brittany (voice)
Bella Thorne Ashley Grey
Jason Lee Dave
Matthew Gray Gubler Simon (voice)
Tony Hale Agent Suggs
John Waters First Class Passenger
Kimberly Williams-Paisley Samantha
Jesse McCartney Theodore (voice)
Zeeko Zaki Paparazzi #2
Uzo Aduba TSA Officer
Eddie Steeples Barry
Denitra Isler Ticket Agent
Retta Party Planner
Flula Borg Man Behind Mask
Ryan Kilgore Brass Band Member
Jeremy Ray Taylor Kid
Laura Marano Hotel Babysitter
John Lacy Owner
Ross Bagdasarian, Jr. Characters, Producer, Alvin (singing voice) (uncredited)
Josh Green Miles
Janice Karman Characters, Producer, Theodore / The Chipettes (singing voice) (uncredited)
David DeSantos Maitre'd
Joshua Mikel Wyatt the Pizza Guy
Arnon Milchan Executive Producer
Greg Pitts Pool Attendant
Mark Mothersbaugh Original Music Composer
Peter Lyons Collister Director of Photography
Mark Jeffrey Miller Cab Driver
Mary Claire Hannan Costume Design
Joe Letteri Senior Visual Effects Supervisor
Jack Gill Stunt Coordinator
Charmin Lee Judge
Keith Arthur Bolden Party Cop #2
Adam Sztykiel Writer
Brice R. Parker Visual Effects Producer
Elyse Dufour Access Hollywood Reporter
Sheila Jaffe Casting
Matthew O'Callaghan Animation Supervisor
Walt Becker Director
Candace B. Harris Airline Ticket Agent
John H. Starke Executive Producer
Paul D. Kelly Supervising Art Director
Kevin Wayne Large Cowboy
Karen Rosenfelt Executive Producer
Katrine Hoyt Shelbourne Hotel Guest (voice) (uncredited)
Leticia Jimenez Second Record Executive
Jeff Carson Music Editor
Sean Noel Walker CG Supervisor
Phillip Leonhardt CG Supervisor
Justin Miles Young Employee
Manish Raval Music Supervisor
Onira Tarés First Record Executive
Steve Dubin Visual Effects Producer
Jackie Burch Casting
John Berri Visual Effects Editor
Stefan Gordy DJ at Party
Hakim Callender Passing Record Executive
Kit Hoover Access Hollywood Anchor
Frank Galline Set Decoration
Richard Holland Production Design
Galen Goodpaster Supervising Sound Editor
Tom Wolfe Music Supervisor
Grady Allen Bishop Stunt Driver
Thomas E. Ackerman Second Unit Director
Daniel Hargrave Stunts
Jim Harrison Music Editor
Parker Wierling Miniature Golf Boy
Jennifer Teves Associate Producer