Jennifer Coolidge Ms. Price
Anna Faris Jeanette (voice)
Justin Long Alvin (voice)
Tony Hale Agent Suggs
Jason Lee Dave
Kaley Cuoco Eleanor (voice)
Uzo Aduba TSA Officer
Bella Thorne Ashley Grey
Christina Applegate Brittany (voice)
Kimberly Williams-Paisley Samantha
Matthew Gray Gubler Simon (voice)
Zeeko Zaki Paparazzi #2
Jeremy Ray Taylor Kid
Laura Marano Hotel Babysitter
Flula Borg Man Behind Mask
Retta Party Planner
Denitra Isler Ticket Agent
John Waters First Class Passenger
Joshua Mikel Wyatt the Pizza Guy
Arnon Milchan Executive Producer
Jesse McCartney Theodore (voice)
Jack Gill Stunt Coordinator
Joe Letteri Senior Visual Effects Supervisor
Kevin Wayne Large Cowboy
Adam Sztykiel Writer
Eddie Steeples Barry
Charmin Lee Judge
Keith Arthur Bolden Party Cop #2
Justin Miles Young Employee
Matthew O'Callaghan Animation Supervisor
Walt Becker Director
Mark Mothersbaugh Original Music Composer
Ryan Kilgore Brass Band Member
Manish Raval Music Supervisor
Tracy Goode Bus Driver
Peter Lyons Collister Director of Photography
Alana Da Fonseca Executive Music Producer
Ross Bagdasarian, Jr. Characters, Producer, Alvin (singing voice) (uncredited)
John Lacy Owner
Katrine Hoyt Shelbourne Hotel Guest (voice) (uncredited)
Mark Jeffrey Miller Cab Driver
Jackie Burch Casting
Josh Green Miles
Onira Tarés First Record Executive
Janice Karman Characters, Producer, Theodore / The Chipettes (singing voice) (uncredited)
Doug Jackson Supervising Sound Editor
John H. Starke Executive Producer
Daniel DiPrima Music Editor
David DeSantos Maitre'd
Candace B. Harris Airline Ticket Agent
Daniel Hargrave Stunts
Parker Wierling Miniature Golf Boy
Mary Claire Hannan Costume Design
Tom Wolfe Music Supervisor
Sheila Jaffe Casting
Phillip Leonhardt CG Supervisor
Karen Rosenfelt Executive Producer
Ryan Folsey Editor
Leticia Jimenez Second Record Executive
Andrew Dorfman Music Editor
Brice R. Parker Visual Effects Producer
Greg Pitts Pool Attendant
Edwin Rivera Visual Effects Supervisor
Steve Dubin Visual Effects Producer
Jeff Carson Music Editor
Thomas E. Ackerman Second Unit Director
David McKimmie Associate Producer
Mike Senior Paparazzi #1
Grady Allen Bishop Stunt Driver
Stevie Martin Makeup Artist
Paul D. Kelly Supervising Art Director
Jennifer Teves Associate Producer