Robert De Niro Senator John McLaughlin
Jessica Alba Sartana Rivera
Michelle Rodriguez Luz
Steven Seagal Rogelio Torrez
Danny Trejo Machete
Lindsay Lohan April Booth
Jeff Fahey Michael Booth
Stacy Keach Doc Franklin
Shea Whigham Sniper
Cheech Marin Padre Cortez
Don Johnson Von Jackson
Daryl Sabara Julio
Robert Rodriguez Director, Producer, Editor, Writer
James Parks Edgar McGraw
Tommy Nix Dishwasher
Juan Gabriel Pareja Rico
Electra Avellan Nurse Mona
Tom Savini Osiris Amanpour
Mary Vernieu Casting
Nina Leon Machete's Wife
Cheryl Wheeler Duncan Stunts
Nimród Antal Booth's Bodyguard #1
Tito Larriva Culebra Cruzado
Jason Douglas Patrolman #1
Billy Blair Von's Henchman
Mark Norby Stunts
Edgar Arreola Dishwasher
Troy Robinson Stunts
Chris Warner Hospital Security Guard
Elise Avellan Nurse Lisa
Ara Celi Reporter
Mayra Leal Chica (Naked Girl)
Jeremy Fitzgerald Stunts
Vic Trevino Federale Officer
Christopher M. Campos Stunts
Elizabeth Avellan Producer
Tina Rodriguez Tristana
Alcides Dias Booth's Bodyguard #2
Dimitrius Pulido Bodyguard #3
Álvaro Rodríguez Writer
Ashok Amritraj Executive Producer
Roland Ruiz Luis
Gilbert Trejo Jorge
Ethan Maniquis Director
Ermahn Ospina Makeup Department Head
Doran Ingram Billy's Henchman
Jim Henry Guard
Alicia Rachel Marek June
Rebecca Rodriguez Editor
Myles Nestel Executive Producer
Russell Towery Stunt Coordinator
P.K. Munson First Assistant "B" Camera
Greg Ingram Cristos
Mark Chavarria Stunts
Joseph T. Campos Stunts
J.C. Cantu Casting
Jimmy Lindsey Director of Photography
Rick Schwartz Producer
Todd Smiley Gaffer
Scottie Jefferies Bodyguard #4
Joe Rivera Hair Department Head
Hugo Perez Van Driver
Debbie Cortez Haber Art Department Coordinator
Ferrell A. Shinnick Key Grip
Bart Brown Set Decoration
Rico Torres Still Photographer
Matt Harshbarger Second Assistant "A" Camera
Sebastian Vega First Assistant "A" Camera
Marci Madison Nurse Fine
Raul Mello Rigging Gaffer
Felix Sabates Doc Felix
Scott A. Reeder Property Master