Zoe Saldaña Maria (voice)
Channing Tatum Joaquin (voice)
Ron Perlman Xibalba (voice)
Danny Trejo Skeleton Luis (voice)
Guillermo del Toro Producer, Land of Remembered Captain's Wife (voice)
Diego Luna Manolo (voice)
Ice Cube Candle Maker (voice)
Ana de la Reguera Skeleton Carmen (voice)
Christina Applegate Mary Beth (voice)
Grey DeLisle Grandma (voice)
Cheech Marin Pancho Rodriguez (voice)
Eric Bauza Father Domingo / Cave Guardian (voice)
Carlos Alazraqui General Posada / Dali / Chuy (voice)
Héctor Elizondo Carlos Sanchez (voice)
Eugenio Derbez Chato (voice)
Miguel Sandoval Land of Remembered Captain (voice)
Kate del Castillo La Muerte (voice)
Gabriel Iglesias Pepe Rodriguez (voice)
Sandra Echeverría Claudia (voice)
Aron Warner Executive Producer, Thomas (voice)
Plácido Domingo Skeleton Jorge (voice)
Troy Evans Old Man Hemingway (voice)
Sandra Equihua Character Designer, Scardelita (voice)
Arthur Ortiz Additional Voices (voice)
Anjelah Johnson-Reyes Adelita / Nina (voice)
Angélica María Sister Ana (voice)
Gustavo Santaolalla Original Music Composer
Jessie Pariseau First Assistant Sound Editor
Moosie Drier Additional Voices (voice)
Eva Bella Additional Voices (voice)
Blake Collins Foley
Cullen McCarthy Additional Voices (voice)
James Ashwill Foley
Vicki Davis Additional Voices (voice)
Dan O'Connell Foley
Tim Walston Sound Designer
Al Rodrigo Additional Voices (voice)
Rachel Bolt Musician
Jonathan Nichols-Navarro Additional Voices (voice)
Steve Mair Musician
Michael Miller ADR & Dubbing
Beau Borders Sound Re-Recording Mixer
Newell Alexander Additional Voices (voice)
Steve Alterman Additional Voices (voice)
John T. Cucci Foley
Jorge R. Gutierrez Skeleton Carmelo (voice), Character Designer, Playback Singer, Director, Writer, Additional Music
David Cowgill Additional Voices (voice)
Mark Mangini Additional Sound Re-Recording Mixer
Lynnanne Zager Additional Voices (voice)
Doug Langdale Writer
Elijah Rodriguez Young Joaquin (voice)
Julie Feiner ADR Editor
Katie Rice Storyboard Artist
Ricardo Curtis Head of Story
Elisa Gabrielli Additional Voices (voice)
Steve Cunningham Animation
Casey Stone Scoring Mixer
Richard Miro Additional Voices (voice)
Scott Martin Gershin Supervising Sound Editor
Stephen P. Robinson Sound Designer
Marcelo Tubert Additional Voices (voice)
Rosemary Alexander Additional Voices (voice)
John Houlihan Music Supervisor
Mark Berrow Musician
David Arch Musician
Christian Kaplan Casting
Nicholas Bucknall Musician
Scott Wolf Sound Effects Editor
Gunnar Sizemore Ignacio (voice)
Tonita Castro La Muerte as Old Woman (voice)
Germaine Franco Orchestrator, Additional Music
David Michie Additional Voices (voice)