Zoe Saldaña Maria (voice)
Channing Tatum Joaquin (voice)
Angélica María Sister Ana (voice)
Ron Perlman Xibalba (voice)
Guillermo del Toro Land of the Remembered Captain's Wife (voice), Producer
Christina Applegate Mary Beth (voice)
Eugenio Derbez Chato (voice)
Kate del Castillo La Muerte (voice)
Frank Welker Toro Muerto (voice) (uncredited)
Danny Trejo Skeleton Luis (voice)
Ice Cube Candle Maker (voice)
Grey DeLisle Grandmother (voice) (as Grey Griffin)
Diego Luna Manolo (voice)
Ana de la Reguera Carmen Sánchez (voice)
Cheech Marin Pancho Rodriguez (voice)
Héctor Elizondo Carlos Sanchez (voice)
Carlos Alazraqui General Posada / Dali / Chuy (voice)
Troy Evans Old Man Hemingway (voice)
Miguel Sandoval Land of the Remembered Captain (voice)
Eric Bauza Father Domingo / Cave Guardian (voice)
Gabriel Iglesias Pepe Rodriguez (voice)
Anjelah Johnson-Reyes Adelita / Nina (voice)
Jorge R. Gutierrez Skeleton Carmelo (voice), Character Designer, Additional Music, Director, Writer, Playback Singer
John T. Cucci Foley
Sandra Echeverría Claudia (voice)
Jessie Pariseau First Assistant Sound Editor
Marcelo Tubert Additional Voices (voice)
Aron Warner Thomas (voice), Executive Producer
Dan O'Connell Foley
Moosie Drier Additional Voices (voice)
Scott Martin Gershin Supervising Sound Editor
Jonathan Nichols-Navarro Additional Voices (voice)
Gustavo Santaolalla Original Music Composer
Eva Bella Additional Voices (voice)
Vicki Davis Additional Voices (voice)
Elisa Gabrielli Additional Voices (voice)
Dan Navarro Chakal (voice)
Newell Alexander Additional Voices (voice)
David Cowgill Additional Voices (voice)
Christopher T. Welch ADR Editor
Doug Langdale Writer
Ruth Zalduondo Additional Voices (voice)
John Guentner Foley
Elijah Rodriguez Young Joaquin
Al Rodrigo Additional Voices (voice)
Plácido Domingo Skeleton Jorge (voice)
Blake Collins Foley
Lynnanne Zager Additional Voices (voice)
Tonita Castro La Muerte as Old Woman (voice)
James Ashwill Foley
Stephen P. Robinson Sound Designer
Beau Borders Sound Re-Recording Mixer
Rosemary Alexander Additional Voices (voice)
Scott Wolf Sound Effects Editor
Rachel Bolt Musician
Andy Koyama Sound Re-Recording Mixer
Julie Feiner ADR Editor
Tim Davies Conductor
Jesse Johnstone Sound Recordist
Casey Stone Scoring Mixer
Richard Miro Additional Voices (voice)
Charles Martin Inouye Music Editor
Michael Miller ADR & Dubbing
Mark Mangini Additional Sound Re-Recording Mixer
Carlos Sotolongo ADR & Dubbing
Morgan R. Kelly Animation
Cullen McCarthy Additional Voices (voice)
Jeff Carson Music Editor
Andy King Sound Re-Recording Mixer
John Houlihan Music Supervisor
Mark Berrow Musician
Tim Walston Sound Designer