Sandra Bullock Scarlet Overkill (voice)
Allison Janney Madge Nelson (voice)
Jon Hamm Herb Overkill (voice)
Hiroyuki Sanada Sumo Villain (voice)
Steve Carell Young Gru (voice)
Tara Strong Additional Voices (voice)
Michael Keaton Walter Nelson (voice)
Jim Cummings Additional Voices (voice)
Geoffrey Rush Narrator (voice)
Bob Bergen Additional Voices (voice)
Mindy Sterling Additional Voices (voice)
Steve Coogan Professor Flux / Tower Guard (voice)
Carlos Alazraqui Additional Voices (voice)
Lori Alan Additional Voices (voice)
Pierre Coffin Minions (voice), Director
Jennifer Saunders The Queen (voice)
Andy Nyman Additional Voices (voice)
Katy Mixon Tina (voice)
Ava Acres Additional Voices (voice)
Laraine Newman Additional Voices (voice)
Keith Ferguson Additional Voices (voice)
Cole Sand Additional Voices (voice)
Bill Farmer Additional Voices (voice)
Brian Lynch Writer
John Kassir Additional Voices (voice)
Ken Daurio Characters
Kyle Balda Additional Voices (voice), Director
Jess Harnell Additional Voices (voice)
Mickie McGowan Additional Voices (voice)
Chris Renaud Executive Producer
Glenn McCoy Additional Storyboarding
Cinco Paul Characters
Eric Favela Additional Storyboarding
Adam Van Wyk Additional Storyboarding
Lewis Macleod Additional Voices (voice)
Christopher Ragland Additional Voices (voice)
Brett Hoffman Associate Producer
Gary Rizzo Sound Re-Recording Mixer
Cal Brunker Additional Storyboarding
Danny Mann Additional Voices (voice)
Jim Ward Additional Voices (voice)
Brian T. Delaney Additional Voices (voice)
Serguei Kouchnerov Story Artist
John Cygan Additional Voices (voice)
Mona Marshall Additional Voices (voice)
Dennis Leonard Supervising Sound Editor
Jan Rabson Additional Voices (voice)
Chris Meledandri Producer
Guylo Homsy Layout Supervisor
Jonathan del Val Supervising Animator
Mark O'Hare Additional Storyboarding
Alexander Polinsky Additional Voices (voice)
Charlie Hayes Additional Voices (voice)
Claire Dodgson Editor
Robert Taylor Associate Producer
Paul Thornley News Reporter (voice)
Sherry Lynn Additional Voices (voice)
Chris Scarabosio Sound Re-Recording Mixer, Sound Designer
David Feiss Additional Storyboarding
Heitor Pereira Original Music Composer
Antoine Ettori Story Artist
William Vanderpuye Additional Voices (voice)
Janet Healy Producer
Zachary Alexander Rice Additional Voices (voice)
Eric Guillon Character Designer, Production Design
Carter Goodrich Character Designer
Josh Gold Sound Effects Editor
Colette Whitaker Additional Voices (voice)
Ronni Brown Foley Artist
Daniel Barker Additional Voices (voice)
Sean England Foley Artist
Michael Beattie VNC Announcer / Walter Jr. (voice)