Quentin Tarantino Rapist #1, Producer
Josh Brolin Dr. William Block
Bruce Willis Lieutenant Muldoon
Harvey Weinstein Executive Producer
Julio Oscar Mechoso Romey
Danny Trejo Machete
Jeff Fahey J.T. Hague
Rose McGowan Cherry Darling
Freddy Rodríguez Wray
Marley Shelton Dr. Dakota Block
Michael Biehn Sheriff Hague
Robert Rodriguez Director, Screenplay, Director of Photography, Editor, Producer, Original Music Composer, One of Abby's Henchmen (uncredited), Visual Effects Supervisor, Sound Mix Technician
Tim Trella Stunts
Cheech Marin Priest
Zoë Bell Stunts, Sicko Eating Paramedic #2 (uncredited)
Nicky Katt Joe
Greg Nicotero Special Effects
Rebel Rodriguez Tony Block
Jeanette Scott Set Decoration
Tom Savini Deputy Tolo
Corey Burton Additional Narrator (voice)
Michael Parks Earl McGraw
Electra Avellan Babysitter Twin #1
Elizabeth Avellan Producer
Hank Amos Stunt Coordinator
William Jacobs Sound Effects Editor
Sandra Lee Gimpel Stunts
Jeff 'JJ' Dashnaw Stunts
Mary Vernieu Casting
Norman Howell Stunts
Naveen Andrews Abby
Carlos Gallardo Deputy Carlos
Sally Menke Editor
Elise Avellan Babysitter Twin #2
Garrett Warren Stunts
Jennifer Caputo Stunts
Gregory Kelly Rapist #2
Jimmy N. Roberts Stunts
Troy Robinson Soldier #1, Stunts
Jason Douglas Lewis
Caylah Eddleblute Art Direction
Buddy Joe Hooker Stunts
Billy D. Lucas Stunts
Jeff Imada Stunts
Oakley Lehman Stunts
Derek Southers Soldier #2
Fergie Tammy Visan
Bob Weinstein Executive Producer
Charles Maynes Sound Effects Editor
Jon H. Epstein Stunts
Keith Campbell Stunts
Emmy Robbin Hot Female Deputy (uncredited)
Felix Sabates Dr. Felix
Tommy Nix Paramedic Nixer
Angelo Palazzo Sound Effects Editor
Luz María Rojas Line Producer
Sandra Condito Executive Producer
Lance Gilbert Stunts
Russell Towery Stunt Coordinator
Nina Proctor Costume Design
Becki Drake Makeup Artist
Tom Proper Associate Producer
Steve Joyner Production Design
Tim Rakoczy Supervising Sound Editor
Jerili Romeo Ramona McGraw
Dick Hancock Stunts
Skip Reissig Skip
Cecilia Conti Paramedic Cecil
Erica Steinberg Producer
Paula Fairfield Sound Effects Editor
Carla Murray Sound Effects Editor
Bill Scott Line Producer