Angelina Jolie Olympias
Colin Farrell Alexander
Anthony Hopkins Old Ptolemy
Jared Leto Hephaistion
Christopher Plummer Aristotle
Jonathan Rhys Meyers Cassander
Joseph Morgan Philotas
Rosario Dawson Roxane
Val Kilmer Philip
Fiona O'Shaughnessy Nurse
Michael Dixon Campfire Soldier
Jemma Scott-Knox-Gore Contact Lens Technician
Toby Kebbell Pausanius
Abbie Hirst Octavia (uncredited)
Jason Croot Peasant (uncredited)
Mick Lally Horse Seller
Raz Degan Darius III
Oliver Stone Macedonian Soldier at Zeus Statue (uncredited), Director, Screenplay, Producer
Jaran Ngamdee Indian Prince
Brian Blessed Wrestling Trainer
Michelle Lukes Roxane Dancer
Thomas J. Nordberg Editor
Elliot Cowan Ptolemy
Ian Beattie Antigonus
Mark Bennett Casting
Tim Pounds-Cornish Visual Effects Editor
W.C. 'Chunky' Huse Key Grip
Olivier Chiavassa Digital Intermediate
Benjamín Benítez Amato (uncredited)
Paul Conway Supervising ADR Editor
Connor Paolo Young Alexander
Bin Bunluerit Indian King
Annelise Hesme Stateira
Charles Haigh Aristander (uncredited)
Christopher Kyle Screenplay
Deborah Maxwell Dion Casting Associate
Rory McCann Crateros
Stuart Rose Art Direction
Tim Pigott-Smith Omen Reader
Neil Jackson Perdiccas
Pierre Grunstein Executive Producer
Sean Button Stunts
Féodor Atkine Roxane's Father
Gary Stretch Cleitus
Julian Caldow Conceptual Illustrator
Séverine De Wever Visual Effects Coordinator
Joyce Menger Visual Effects Producer
Nick Dunning Attalus
John Kavanagh Parmenion
Stephen Miles Assistant Costume Designer
Dale Dye Macedonian Veteran at Hyphasis Speech (uncredited), Second Unit Director
Peter Gleaves ADR Mixer
Julien Bourdeau Assistant Sound Editor
Laeta Kalogridis Screenplay
Mohamed Rakaa Leadman
Ian Foster Camera Operator
Jeremy Woodhead Makeup Designer
Nic Raine Orchestrator, Conductor
Garrett Lombard Leonnatus
Benny Maslov Bagoas Dancer
Lucinda Syson Casting
David Leon Hermolaous (uncredited)
Gary Powell Stunt Coordinator
Brian McGrath Doctor
Chaiyan Chunsuttiwat Art Direction
Wayne Leach Rigging Gaffer
Dean Morris Assistant Camera
Mark Southworth Stunts
John Gamble First Assistant Camera
Yann Mari Faget Second Assistant Director
Jessie Kamm Young Alexander
Desmond O'Neill Acolyte at Sacrifice (uncredited)