Peter Weller Batman / Bruce Wayne (voice)
Tara Strong Michelle / Young Bruce Wayne / Kevin Ridley / Anchor Trish / Additional Voices (voice)
Frank Welker Mayor Stevenson / Weather Man (voice)
Dee Bradley Baker Don / Fat Mutant / Additional Voices (voice)
Grey DeLisle Anchor Carla / Female Mutant (voice)
Ariel Winter Robin / Carrie Kelley (voice)
Michael McKean Dr. Bartholomew Wolper (voice)
Carlos Alazraqui Hernando / TV Host (voice)
Michael Emerson Joker (voice)
Yuri Lowenthal Son of Batman / Rookie Police Officer (voice)
Paget Brewster Lana Lang (voice)
Maurice LaMarche Dr. Willing / News Anchor (voice)
David Selby James Gordon (voice)
Richard Doyle The Mayor (voice)
Wade Williams Harvey Dent / Two-Face (voice)
James Arnold Taylor Mr. Hudson / Spud / Additional Voices (voice)
Gary Anthony Williams Mutant Leader / Anchor Bill (voice)
Rob Paulsen Jeff Adams (voice)
Sam McMurray Anchor Ted (voice)
Bruce Timm Thomas Wayne (voice), Executive Producer
James Patrick Stuart Murray (voice)
Maria Canals-Barrera Yindel (voice)
Frank Miller Graphic Novel Illustrator, Novel
Jay Oliva Director
Cathy Cavadini Joanie / Woman with Hot Dog (voice)
Jim Wise Femur (voice)
Alan Burnett Co-Producer
Gwendoline Yeo Lola Chong (voice)
Townsend Coleman Morrie / Civilian (voice)
Sam Register Executive Producer
Greg Eagles Mackie (voice)
Danny Jacobs Merkel (voice)
Gary Anthony Sturgis Silk / Other Spike / Young Mutant (voice)
Bob Goodman Screenplay
Michael Uslan Executive Producer
Benjamin Melniker Executive Producer
Meredith Layne Casting Director
Andrea Romano Woman / Police Dispatch (voice)
Matthew Girardi Visual Effects
Michael Jackson Alfred Pennyworth (voice)
Christopher Drake Original Music Composer
Christopher D. Lozinski Editor
Robert Hargreaves Sound Designer
Paul Bentman Special Effects