Tara Strong Michelle / Young Bruce Wayne / Kevin Ridley / Anchor Trish / Additional Voices (voice)
Michael McKean Dr. Bartholomew Wolper (voice)
Frank Welker Mayor Stevenson / Weather Man (voice)
Michael Emerson Joker (voice)
Paget Brewster Lana Lang (voice)
Wade Williams Harvey Dent / Two-Face (voice)
Dee Bradley Baker Don / Fat Mutant / Additional Voices (voice)
Peter Weller Batman / Bruce Wayne (voice)
James Patrick Stuart Murray (voice)
Ariel Winter Robin / Carrie Kelley (voice)
Grey DeLisle Anchor Carla / Female Mutant (voice)
Yuri Lowenthal Son of Batman / Rookie Police Officer (voice)
Maurice LaMarche Dr. Willing / News Anchor (voice)
David Selby James Gordon (voice)
Carlos Alazraqui Hernando / TV Host (voice)
Andrea Romano Woman / Police Dispatch (voice)
Richard Doyle The Mayor (voice)
Benjamin Melniker Executive Producer
Bruce Timm Thomas Wayne (voice), Executive Producer
Maria Canals-Barrera Yindel (voice)
Sam McMurray Anchor Ted (voice)
Gary Anthony Williams Mutant Leader / Anchor Bill (voice)
Frank Miller Graphic Novel Illustrator, Novel
Jay Oliva Director
James Arnold Taylor Mr. Hudson / Spud / Additional Voices (voice)
Rob Paulsen Jeff Adams (voice)
Robert Hargreaves Sound Designer
Gwendoline Yeo Lola Chong (voice)
Danny Jacobs Merkel (voice)
Cathy Cavadini Joanie / Woman with Hot Dog (voice)
Sam Register Executive Producer
Greg Eagles Mackie (voice)
Townsend Coleman Morrie / Civilian (voice)
Alan Burnett Co-Producer
Gary Anthony Sturgis Silk / Other Spike / Young Mutant (voice)
Jim Wise Femur (voice)
Michael Uslan Executive Producer
Bob Goodman Screenplay
Christopher Drake Original Music Composer
Meredith Layne Casting Director
Matthew Girardi Visual Effects
Christopher D. Lozinski Editor
Michael Jackson Alfred Pennyworth (voice)
Paul Bentman Special Effects