Christopher Lloyd Mr. Clipboard (voice)
Eva Longoria Lady X (voice)
Ed Asner Mr. Leonard (voice)
Charlie Sheen Dex Dogtective (voice)
Jeff Bennett Lieutenant X/Additional Voices (voice)
Christine Baranski Hedda Shopper (voice)
Haylie Duff Sweet Cakes (voice)
Hilary Duff Sunshine Goodness (voice)
Cloris Leachman Brand X Lunch Lady (voice)
Wayne Brady Daredevil Dan (voice)
Daniel Bernhardt Additional Voices (voice)
Larry Miller Vlad Chocool (voice)
Eliza Schneider Sweet Older Lady (voice)
Robert Costanzo Maximilius Moose (voice) (as Bobby Constanza)
Edie McClurg Mrs. Butterworth (voice)
John Bloom Additonal Voices (voice)
Chris Kattan Polar Penguin (voice)
Harvey Fierstein Fat Cat Burglar (voice)
Greg Ellis Hairy Hold (voice)
James Arnold Taylor Dr. Si Nustrix / Additonal Voices (voice)
Jerry Stiller General X (voice)
Sean Catherine Derek Writer, Toddler's Mom (voice)
Bob Bergen Additional Voices (voice)
Jeff Bergman Charlie Tuna (voice)
Martin Klebba General X / Kaptain Krispy (voice)
Joshua Wexler Story, Producer, Hairless Hamster Henchman (voice)
Stephen Stanton Mr. Clean / Lord Flushington / Additional Voices (voice)
Jonathan A. Carlson Production Design
Susan Silo Additional Voices (voice)
Enn Reitel Kung Tofu / Fracois Fromage (voice)
Daniel Franzese Twinkleton (voice)
Greg Eagles Hairless Hamster Henchman (voice)
Shelley Morrison Lola Frutola (voice)
Jimmy Ienner Executive Producer
Brent V. Friedman Writer
Melissa Disney Additional Voices (voice)
Tom Ortenberg Executive Producer
Jason Harris Hairles Hamster Henchman (voice)
Robin Klein Casting
Andrew Ortenberg Ike Kid #3 (voice)
Walter Murphy Original Music Composer
Heidi Klein Casting
George Johnsen Producer, Kaptain Krispy / Hairless Hamster Henchman (voice)
Lawrence Kasanoff Director, Story, Cheasel T. Weasel (voice), Producer, Writer
Eli James Wungo Wasabi (voice)
Craig Paulsen Editor
Robert Engelman Producer
Rebecca Swanson Writer
Ann Hoyt Editor
Sean Rourke Editor
Jennifer Keith Ike Kid #4 / Additional Voices (voice)
Jason Ortenberg Ike Kid #1 (voice)
Robert D. Cain Executive Producer
Ray Mupas Editor
Karen Gallo Messore Blue (voice)
Susan Carter Hall Art Direction
Zachary Liebrich-Johnsen Ike Kid #2 (voice)