Don't Look Up 2021
President Orlean
The Devil Wears Prada 2006
Miranda Priestly
Mamma Mia! Here We Go Again 2018
Donna Sheridan-Carmichael
Mary Poppins Returns 2018
Cousin Topsy
Fantastic Mr. Fox 2009
Felicity Fox (voice)
Mamma Mia! 2008
Donna Sheridan
Into the Woods 2014
Witch
Lemony Snicket's A Series of Unfortunate Events 2004
Josephine Anwhistle
The Laundromat 2019
Ellen Martin / Elena
Florence Foster Jenkins 2016
Florence Foster Jenkins
The Prom 2020
Dee Dee Allen
August: Osage County 2013
Violet Weston
Adaptation. 2002
Susan Orlean
It's Complicated 2009
Jane Adler
Death Becomes Her 1992
Madeline Ashton Menville
The Ant Bully 2006
Queen (voice)
Ricki and the Flash 2015
Ricki Rendazzo
Manhattan 1979
Jill
Hope Springs 2012
Kay
Let Them All Talk 2020
Alice Hughes
Prime 2005
Lisa Metzger
Stuck on You 2003
Meryl Streep (uncredited)
SNL50: The Homecoming Concert 2025
Self
A Prairie Home Companion 2006
Yolanda Johnson
She-Devil 1989
Mary Fisher
Defending Your Life 1991
Julia
Postcards from the Edge 1990
Suzanne Vale
Heartburn 1986
Rachel
In Search of the Sanderson Sisters: A Hocus Pocus Hulaween Takeover 2020
Meryl Streep
Sell/Buy/Date 2022
Executive Producer
The Music of Regret 2006
The Woman
Stuck Together: Bringing Stuck on You to the Screen 2004
Self
Kiss Me, Petruchio 1981
Katherine
The Devil Wears Prada 2 2026
Miranda Priestly
Uncommon Women and Others 1979
Leilah